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    F47E1.20 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 185936, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F47E1.20
    Official Full Name
    C2H2-type domain-containing protein
    Primary source
    WormBase:WBGene00304808
    Locus tag
    CELE_F47E1.20
    See related
    AllianceGenome:WB:WBGene00304808
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human PRDM14 (PR/SET domain 14). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F47E1.20 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (9048957..9054983)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene RGS domain-containing protein Neighboring gene PR/SET domain Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Solute carrier organic anion transporter family member Neighboring gene tRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    C2H2-type domain-containing protein
    NP_001360749.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      9048957..9054983
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373408.2 → NP_001360749.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IJB8
      Conserved Domains (3) summary
      COG5189
      Location:123 → 290
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:241 → 261
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:282 → 306
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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