U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    F47E1.2 Solute carrier organic anion transporter family member [ Caenorhabditis elegans ]

    Gene ID: 181145, updated on 9-Dec-2024

    Summary

    Official Symbol
    F47E1.2
    Official Full Name
    Solute carrier organic anion transporter family member
    Primary source
    WormBase:WBGene00018566
    Locus tag
    CELE_F47E1.2
    See related
    AllianceGenome:WB:WBGene00018566
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Predicted to be active in basolateral plasma membrane. Human ortholog(s) of this gene implicated in bilirubin metabolic disorder and gastrointestinal stromal tumor. Orthologous to several human genes including SLCO3A1 (solute carrier organic anion transporter family member 3A1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See F47E1.2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Sequence:
    Chromosome: X; NC_003284.9 (9057652..9061860)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene Solute carrier organic anion transporter family member Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables sodium-independent organic anion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sodium-independent organic anion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in basolateral plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Solute carrier organic anion transporter family member
    NP_509531.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      9057652..9061860
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077130.8NP_509531.1  Solute carrier organic anion transporter family member [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509531.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20538
      Conserved Domains (4) summary
      cd06174
      Location:892
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      cd01330
      Location:528583
      KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
      TIGR00805
      Location:95715
      oat; sodium-independent organic anion transporter
      cl21472
      Location:274503
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...