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    D2045.8 BTB domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176468, updated on 9-Dec-2024

    Summary

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    Official Symbol
    D2045.8
    Official Full Name
    BTB domain-containing protein
    Primary source
    WormBase:WBGene00008425
    Locus tag
    CELE_D2045.8
    See related
    AllianceGenome:WB:WBGene00008425
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in protein homooligomerization. Orthologous to human TNFAIP1 (TNF alpha induced protein 1); KCTD10 (potassium channel tetramerization domain containing 10); and KCTD13 (potassium channel tetramerization domain containing 13). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See D2045.8 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (10482288..10483943)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Glycosyltransferase 25 family member Neighboring gene non-specific serine/threonine protein kinase Neighboring gene ncRNA Neighboring gene SSD domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3. Xu L, et al. Nature, 2003 Sep 18. PMID 13679922
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BTB domain-containing protein
    NP_499312.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10482288..10483943
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066911.7 → NP_499312.2  BTB domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499312.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18986
      Conserved Domains (1) summary
      cl38908
      Location:7 → 97
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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