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    Tmem242 transmembrane protein 242 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292228, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmem242provided by RGD
    Official Full Name
    transmembrane protein 242provided by RGD
    Primary source
    RGD:1307262
    See related
    EnsemblRapid:ENSRNOG00000016973 AllianceGenome:RGD:1307262
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    C1H6orf35; RGD1307262
    Summary
    Predicted to be involved in mitochondrial proton-transporting ATP synthase complex assembly. Predicted to be located in mitochondrial inner membrane. Orthologous to human TMEM242 (transmembrane protein 242). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 244.8), Kidney (RPKM 155.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem242 in Genome Data Viewer
    Location:
    1q11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (48397865..48424639, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (45992713..46019684, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (46302546..46329885, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134484862 Neighboring gene AT-rich interaction domain 1B Neighboring gene lactate dehydrogenase A-like 6B Neighboring gene uncharacterized LOC120099115 Neighboring gene zinc finger DHHC-type palmitoyltransferase 14

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in mitochondrial proton-transporting ATP synthase complex assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transmembrane protein 242

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001144860.2 → NP_001138332.1  transmembrane protein 242

      See identical proteins and their annotated locations for NP_001138332.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6KNY7, D4A7K0
      Related
      ENSRNOP00000047116.3, ENSRNOT00000046311.5
      Conserved Domains (1) summary
      pfam07096
      Location:15 → 123
      DUF1358; Protein of unknown function (DUF1358)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      48397865..48424639 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039103364.2 → XP_038959292.1  transmembrane protein 242 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZNB1
      Conserved Domains (1) summary
      pfam07096
      Location:15 → 108
      DUF1358; Protein of unknown function (DUF1358)
    Nucleotide Protein Strain
    Heading Accession and Version

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