Fut11 fucosyltransferase 11 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Fut11provided by RGD
Official Full Name: fucosyltransferase 11provided by RGD
Primary source: RGD:628731
See related: EnsemblRapid:ENSRNOG00000009274 AllianceGenome:RGD:628731
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in N-glycan fucosylation. Predicted to be located in Golgi cisterna membrane and Golgi membrane. Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human FUT11 (fucosyltransferase 11). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Lung (RPKM 69.0), Adrenal (RPKM 65.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 15p16

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (3648022..3651582, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (3598768..3602328, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (4031504..4035064, complement)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH139808 (e-PCR)
- UniSTS:221892

RH128878 (e-PCR)
- UniSTS:212186

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables alpha-(1->3)-fucosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables fucosyltransferase activity	ISO Inferred from Sequence Orthology more info
enables fucosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in N-glycan fucosylation	ISO Inferred from Sequence Orthology more info
involved_in N-glycan fucosylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in fucosylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi cisterna membrane	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: alpha-(1,3)-fucosyltransferase 11

Names: alpha3-fucosyltransferase 11; fuc-TXI; fucT-XI; fucosyltransferase 11 (alpha (1,3) fucosyltransferase); fucosyltransferase XI; galactoside 3-L-fucosyltransferase 11

NP_775430.2

EC 2.4.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_173308.2 → NP_775430.2 alpha-(1,3)-fucosyltransferase 11 precursor

See identical proteins and their annotated locations for NP_775430.2

Status: PROVISIONAL

Source sequence(s)

BC079316

UniProtKB/Swiss-Prot

Q68FV3, Q8CG40

UniProtKB/TrEMBL

A6KKP8

Related

ENSRNOP00000012300.1, ENSRNOT00000012300.5

Conserved Domains (2) summary

pfam00852
Location:217 → 356

Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term

pfam17039
Location:120 → 181

Glyco_tran_10_N; Fucosyltransferase, N-terminal