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    Apoc4 apolipoprotein C4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680551, updated on 27-Nov-2024

    Summary

    Official Symbol
    Apoc4provided by RGD
    Official Full Name
    apolipoprotein C4provided by RGD
    Primary source
    RGD:70959
    See related
    EnsemblRapid:ENSRNOG00000018405 AllianceGenome:RGD:70959
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Acl
    Summary
    Predicted to be involved in positive regulation of sequestering of triglyceride and triglyceride homeostasis. Predicted to be part of high-density lipoprotein particle and very-low-density lipoprotein particle. Orthologous to human APOC4 (apolipoprotein C4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 2950.2) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Apoc4 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (88463713..88467909, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (79335745..79339942, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (80595339..80599525, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene CLPTM1 regulator of GABA type A receptor forward trafficking Neighboring gene uncharacterized LOC134482894 Neighboring gene apolipoprotein C2 Neighboring gene apolipoprotein C1 Neighboring gene apolipoprotein E

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in lipid transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of sequestering of triglyceride IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of sequestering of triglyceride ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in triglyceride homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in triglyceride homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of high-density lipoprotein particle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of high-density lipoprotein particle ISO
    Inferred from Sequence Orthology
    more info
     
    part_of very-low-density lipoprotein particle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of very-low-density lipoprotein particle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    apolipoprotein C-IV
    Names
    ECL
    apo-CIV
    apoC-IV
    apolipoprotein C2 linked
    apolipoprotein CIV
    apolipoprotein E-linked

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109419.1NP_001102889.1  apolipoprotein C-IV precursor

      See identical proteins and their annotated locations for NP_001102889.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473979
      UniProtKB/Swiss-Prot
      P55797
      UniProtKB/TrEMBL
      A6J8R1
      Related
      ENSRNOP00000024832.5, ENSRNOT00000024832.9
      Conserved Domains (1) summary
      pfam15119
      Location:28120
      APOC4; Apolipoprotein C4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      88463713..88467909 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)