Rrs1 ribosome biogenesis regulator 1 homolog [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rrs1provided by RGD
Official Full Name: ribosome biogenesis regulator 1 homologprovided by RGD
Primary source: RGD:1311403
See related: EnsemblRapid:ENSRNOG00000007240 AllianceGenome:RGD:1311403
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable 5S rRNA binding activity. Predicted to be involved in several processes, including mitotic metaphase chromosome alignment; protein localization to nucleolus; and ribosome biogenesis. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in condensed nuclear chromosome; endoplasmic reticulum; and nucleoplasm. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Orthologous to human RRS1 (ribosome biogenesis regulator 1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 5q11

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	5	NC_086023.1 (14516303..14517936, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	5	NC_051340.1 (9733486..9735119, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	5	NC_005104.4 (9430710..9432343, complement)

Chromosome 5 - NC_086023.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables 5S rRNA binding	ISO Inferred from Sequence Orthology more info
enables 5S rRNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within hematopoietic progenitor cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in mitotic metaphase chromosome alignment	ISO Inferred from Sequence Orthology more info
involved_in protein localization to nucleolus	ISO Inferred from Sequence Orthology more info
involved_in protein localization to nucleolus	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of signal transduction by p53 class mediator	ISO Inferred from Sequence Orthology more info
involved_in regulation of signal transduction by p53 class mediator	ISS Inferred from Sequence or Structural Similarity more info
involved_in ribosomal large subunit assembly	ISO Inferred from Sequence Orthology more info
involved_in ribosomal large subunit assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in ribosomal large subunit biogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal large subunit biogenesis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in condensed nuclear chromosome	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
part_of preribosome, large subunit precursor	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ribosome biogenesis regulatory protein homolog

Names: RRS1 ribosome biogenesis regulator homolog; ribosome biogenesis regulator homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.