Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cacng6provided by RGD
Official Full Name: calcium voltage-gated channel auxiliary subunit gamma 6provided by RGD
Primary source: RGD:628806
See related: EnsemblRapid:ENSRNOG00000063051 AllianceGenome:RGD:628806
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable calcium channel regulator activity. Predicted to be involved in regulation of calcium ion transmembrane transport via high voltage-gated calcium channel. Predicted to be part of L-type voltage-gated calcium channel complex. Human ortholog(s) of this gene implicated in aspirin-induced respiratory disease. Orthologous to human CACNG6 (calcium voltage-gated channel auxiliary subunit gamma 6). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Muscle (RPKM 160.4) and Heart (RPKM 25.5) See more
Orthologs: human mouse all
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Genomic context

Location:: 1q12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (74648342..74663351, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (65732910..65747377, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (64307684..64322124, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables calcium channel activity	IEA Inferred from Electronic Annotation more info
enables calcium channel regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables calcium channel regulator activity	ISO Inferred from Sequence Orthology more info
enables calcium channel regulator activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in calcium ion transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of L-type voltage-gated calcium channel complex	IBA Inferred from Biological aspect of Ancestor more info
part_of L-type voltage-gated calcium channel complex	ISO Inferred from Sequence Orthology more info
part_of L-type voltage-gated calcium channel complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: voltage-dependent calcium channel gamma-6 subunit

Names: calcium channel, voltage-dependent, gamma subunit 6; neuronal voltage-gated calcium channel gamma-6 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.