U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Lrrc15 leucine rich repeat containing 15 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 246296, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lrrc15provided by RGD
    Official Full Name
    leucine rich repeat containing 15provided by RGD
    Primary source
    RGD:70551
    See related
    EnsemblRapid:ENSRNOG00000068415 AllianceGenome:RGD:70551
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Lib
    Summary
    Predicted to enable several functions, including fibronectin binding activity; laminin binding activity; and protein sequestering activity. Predicted to be involved in several processes, including negative regulation of protein localization to plasma membrane; negative regulation of viral entry into host cell; and receptor-mediated virion attachment to host cell. Located in cell surface. Orthologous to human LRRC15 (leucine rich repeat containing 15). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 2.8), Uterus (RPKM 1.9) and 5 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Lrrc15 in Genome Data Viewer
    Location:
    11q22
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (83974708..83989157)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (70469817..70484268)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (74040846..74052179)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S26, pseudogene 13 Neighboring gene ATPase 13A3 Neighboring gene glycoprotein V (platelet) Neighboring gene carboxypeptidase N subunit 2 Neighboring gene uncharacterized LOC134480928

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables collagen binding  
    enables collagen binding  
    enables fibronectin binding  
    enables fibronectin binding  
    enables laminin binding  
    enables laminin binding  
    enables protein sequestering activity  
    enables protein sequestering activity  
    Component Evidence Code Pubs
    located_in apical plasma membrane  
    is_active_in apical plasma membrane  
    located_in cell surface PubMed 
    located_in collagen-containing extracellular matrix  
    located_in collagen-containing extracellular matrix  
    located_in plasma membrane  
    located_in plasma membrane  

    General protein information

    Preferred Names
    leucine-rich repeat-containing protein 15
    Names
    leucine-rich repeat protein induced by amyloid-beta
    leucine-rich repeat protein induced by beta-amyloid
    rLib

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145083.2NP_659551.2  leucine-rich repeat-containing protein 15 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/Swiss-Prot
      Q8R5M3
      UniProtKB/TrEMBL
      A6JRV2, M0R476
      Related
      ENSRNOP00000091199.1, ENSRNOT00000095941.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      83974708..83989157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    External link. Please review our privacy policy.