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    Gosr1 golgi SNAP receptor complex member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 94189, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gosr1provided by RGD
    Official Full Name
    golgi SNAP receptor complex member 1provided by RGD
    Primary source
    RGD:71093
    See related
    EnsemblRapid:ENSRNOG00000070572 AllianceGenome:RGD:71093
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    p28; GOS28
    Summary
    Predicted to enable SNAP receptor activity. Acts upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus and membrane. Orthologous to human GOSR1 (golgi SNAP receptor complex member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 122.3), Adrenal (RPKM 113.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Gosr1 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (62068662..62105442, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (61570499..61607287, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (63405526..63442257)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene basic helix-loop-helix family, member a9 Neighboring gene trafficking regulator of GLUT4 (SLC2A4) 1 Neighboring gene high mobility group nucleosome binding domain 1, pseudogene 5 Neighboring gene uncharacterized LOC134480825 Neighboring gene carboxypeptidase D

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables SNAP receptor activity  
    enables SNAP receptor activity  
    enables protein binding PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus PubMed 
    located_in Golgi apparatus  
    is_active_in Golgi medial cisterna  
    is_active_in Golgi membrane  
    located_in Golgi membrane  
    located_in Golgi membrane  
    part_of SNARE complex  
    located_in cis-Golgi network  
    located_in cytosol  
    located_in membrane PubMed 

    General protein information

    Preferred Names
    Golgi SNAP receptor complex member 1
    Names
    28 kDa Golgi SNARE protein
    28 kDa cis-Golgi SNARE p28
    GOS-28
    cis-Golgi p28 (p28)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053584.2NP_446036.1  Golgi SNAP receptor complex member 1

      See identical proteins and their annotated locations for NP_446036.1

      Status: VALIDATED

      Source sequence(s)
      CA338781, CA512572, CB583047, CB712832, CB789285, U49099
      UniProtKB/Swiss-Prot
      A0JN01, Q62931
      UniProtKB/TrEMBL
      A0A8I6A6P3, A6HGW3
      Related
      ENSRNOP00000082876.3, ENSRNOT00000107339.3
      Conserved Domains (1) summary
      cd15864
      Location:160225
      SNARE_GS28; SNARE motif of GS28

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      62068662..62105442 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006246914.4XP_006246976.1  Golgi SNAP receptor complex member 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A6P3
      Conserved Domains (1) summary
      cd15864
      Location:158223
      SNARE_GS28; SNARE motif of GS28
    2. XM_008768132.4XP_008766354.1  Golgi SNAP receptor complex member 1 isoform X2

      Conserved Domains (1) summary
      cd15864
      Location:95160
      SNARE_GS28; SNARE motif of GS28
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