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    Cystm1 cysteine-rich transmembrane module containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100363310, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Cystm1provided by RGD
    Official Full Name
    cysteine-rich transmembrane module containing 1provided by RGD
    Primary source
    RGD:2323233
    See related
    EnsemblRapid:ENSRNOG00000018775 AllianceGenome:RGD:2323233
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in membrane. Orthologous to human CYSTM1 (cysteine rich transmembrane module containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 258.9), Kidney (RPKM 203.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cystm1 in Genome Data Viewer
    Location:
    18p11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (28219861..28287574)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (27945862..28013509)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (29165206..29233351)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098187 Neighboring gene purine rich element binding protein A Neighboring gene IgA-inducing protein Neighboring gene prefoldin subunit 1 Neighboring gene heparin-binding EGF-like growth factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
    3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cysteine-rich and transmembrane domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402495.1 → NP_001389424.1  cysteine-rich and transmembrane domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      A0A8I5ZQ00, A6J307
      Related
      ENSRNOP00000080522.1, ENSRNOT00000094556.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      28219861..28287574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006254621.5 → XP_006254683.1  cysteine-rich and transmembrane domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006254683.1

    2. XM_006254622.4 → XP_006254684.1  cysteine-rich and transmembrane domain-containing protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006254684.1

      Related
      ENSRNOP00000025495.5, ENSRNOT00000025495.9
      Conserved Domains (1) summary
      pfam12734
      Location:93 → 130
      CYSTM; Cysteine-rich TM module stress tolerance

    3. XM_039097367.2 → XP_038953295.1  cysteine-rich and transmembrane domain-containing protein 1 isoform X4

    4. XM_039097366.2 → XP_038953294.1  cysteine-rich and transmembrane domain-containing protein 1 isoform X3

    5. XM_063277049.1 → XP_063133119.1  cysteine-rich and transmembrane domain-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      A6J308, D4A713
      Related
      ENSRNOP00000061418.1, ENSRNOT00000068085.5
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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