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    NAC042 NAC domain containing protein 42 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818902, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NAC042
    Official Full Name
    NAC domain containing protein 42
    Primary source
    TAIR:AT2G43000
    Locus tag
    AT2G43000
    See related
    Araport:AT2G43000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    anac042; ANAC042; F23E6.1; F23E6_1; JUB1; JUNGBRUNNEN 1; NAC domain containing protein 42
    Summary
    Encodes a NAC transcription factor induced by hydrogen peroxide (H2O2. Involved in senescence. Over expression of the gene strongly delays senescence and enhances tolerance to various abiotic stresses.
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    Genomic context

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    See NAC042 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (17880457..17882636, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene myosin-G heavy chain-like protein Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene ncRNA Neighboring gene phytochrome interacting factor 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. JUNGBRUNNEN1 Confers Drought Tolerance Downstream of the HD-Zip I Transcription Factor AtHB13. Ebrahimian-Motlagh S, et al. Front Plant Sci, 2017. PMID 29326734, Free PMC Article
    2. Arabidopsis NAC transcription factor JUB1 regulates GA/BR metabolism and signalling. Shahnejat-Bushehri S, et al. Nat Plants, 2016 Feb 29. PMID 27249348
    3. JUNGBRUNNEN1, a reactive oxygen species-responsive NAC transcription factor, regulates longevity in Arabidopsis. Wu A, et al. Plant Cell, 2012 Feb. PMID 22345491, Free PMC Article
    4. Identification and characterization of ANAC042, a transcription factor family gene involved in the regulation of camalexin biosynthesis in Arabidopsis. Saga H, et al. Mol Plant Microbe Interact, 2012 May. PMID 22295908
    5. The HB40-JUB1 transcriptional regulatory network controls gibberellin homeostasis in Arabidopsis. Dong S, et al. Mol Plant, 2022 Feb 7. PMID 34728415

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The HB40-JUB1 transcriptional regulatory network controls gibberellin homeostasis in Arabidopsis.
      Title: The HB40-JUB1 transcriptional regulatory network controls gibberellin homeostasis in Arabidopsis.
    2. Results show that overexpression of JUB1 in transgenic Arabidopsis enhances tolerance to drought stress in addition to tolerance towards heat and salinity stress.
      Title: JUNGBRUNNEN1 Confers Drought Tolerance Downstream of the HD-Zip I Transcription Factor AtHB13.
    3. JUB1 forms the core of a robust regulatory module that triggers DELLA accumulation, thereby restricting cell elongation while concomitantly enhancing stress tolerance.
      Title: Arabidopsis NAC transcription factor JUB1 regulates GA/BR metabolism and signalling.
    4. JUB1, a core element of the Gibberellic acid - brassinosteroid (BR) - DELLA regulatory module, functions as a negative regulator of defense responses against Pseudomonas syringae pv. tomato DC3000 (Pst DC3000) and mediates the crosstalk between growth and immunity.
      Title: JUB1 suppresses Pseudomonas syringae-induced defense responses through accumulation of DELLA proteins.
    5. ANAC042, a member of the NAM, ATAF1/2, and CUC2 (NAC) transcription factor family genes, is involved in camalexin biosynthesis induction.
      Title: Identification and characterization of ANAC042, a transcription factor family gene involved in the regulation of camalexin biosynthesis in Arabidopsis.
    6. JUB1 is a reactive oxygen species-responsive NAC transcription factor that promotes leaf longevity.
      Title: JUNGBRUNNEN1, a reactive oxygen species-responsive NAC transcription factor, regulates longevity in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001337006.1
    NM_129861.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within anthocyanin-containing compound biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within camalexin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within hyperosmotic salinity response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within proline biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of reactive oxygen species metabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within trehalose biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    NAC domain containing protein 42
    NP_181828.1
    • NAC domain containing protein 42 (NAC042); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: multicellular organismal development, regulation of transcription; LOCATED IN: cellular_component unknown; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: No apical meristem (NAM) protein (InterPro:IPR003441); BEST Arabidopsis thaliana protein match is: NAC (No Apical Meristem) domain transcriptional regulator superfamily protein (TAIR:AT3G12910.1); Has 2932 Blast hits to 2927 proteins in 75 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 2932; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17880457..17882636 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129861.3 → NP_181828.1  NAC domain containing protein 42 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181828.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0SV84, Q9SK55
      UniProtKB/TrEMBL
      A0A178VL40, A0A5S9X6K6
      Conserved Domains (1) summary
      pfam02365
      Location:20 → 143
      NAM; No apical meristem (NAM) protein

    2. NM_001337006.1 → NP_001324496.1  NAC domain containing protein 42 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B0B4
      Conserved Domains (1) summary
      pfam02365
      Location:40 → 65
      NAM; No apical meristem (NAM) protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SK55.1

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