ABF4 ABRE binding factor 4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ABF4
Official Full Name: ABRE binding factor 4
Primary source: TAIR:AT3G19290
Locus tag: AT3G19290
See related: Araport:AT3G19290
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ABA-RESPONSIVE ELEMENT BINDING PROTEIN 2; ABRE binding factor 4; AREB2; AtAREB2; MVI11.7
Summary: bZIP transcription factor with specificity for abscisic acid-responsive elements (ABRE). Mediate ABA-dependent stress responses.
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Genomic context

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See ABF4 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 6

Sequence:: Chromosome: 3; NC_003074.8 (6687042..6690123)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The effect of ABRE BINDING FACTOR 4-mediated FYVE1 on salt stress tolerance in Arabidopsis.
Title: The effect of ABRE BINDING FACTOR 4-mediated FYVE1 on salt stress tolerance in Arabidopsis.
ABF3 and ABF4 act with NF-YCs to promote flowering by inducing SOC1 transcription under drought conditions
Title: Arabidopsis ABF3 and ABF4 Transcription Factors Act with the NF-YC Complex to Regulate SOC1 Expression and Mediate Drought-Accelerated Flowering.
Besides enhancing salt stress and drought tolerance, constitutive expression of ABF4 increases tuber yield under normal and stress conditions, enhances storage capability and improves the processing quality of the tubers.
Title: Expression of the Arabidopsis ABF4 gene in potato increases tuber yield, improves tuber quality and enhances salt and drought tolerance.
the role of ABF1/3/4 in det1 germination phenotypes
Title: Role of Arabidopsis ABF1/3/4 during det1 germination in salt and osmotic stress conditions.
ABF2, ABF3, and ABF4 Promote ABA-Mediated Chlorophyll Degradation and Leaf Senescence by Transcriptional Activation of Chlorophyll Catabolic Genes and Senescence-Associated Genes in Arabidopsis
Title: ABF2, ABF3, and ABF4 Promote ABA-Mediated Chlorophyll Degradation and Leaf Senescence by Transcriptional Activation of Chlorophyll Catabolic Genes and Senescence-Associated Genes in Arabidopsis.
Data show that the HD-Zip protein Athb-21 and B-3 AP2/ERF transcription factor ESE1 are interact with the abscisic acid responsive element binding factor AREB2/ABF4, which binds to a G-box absolutely required for expression of the COX5b-1 gene.
Title: Delta subclass HD-Zip proteins and a B-3 AP2/ERF transcription factor interact with promoter elements required for expression of the Arabidopsis cytochrome c oxidase 5b-1 gene.
AREB1, AREB2, and ABF3 are master transcription factors that regulate the ABRE-dependent expression of water-stress responsive genes in ABA signaling in response to water stresses in a cooperative manner.
Title: AREB1, AREB2, and ABF3 are master transcription factors that cooperatively regulate ABRE-dependent ABA signaling involved in drought stress tolerance and require ABA for full activation.
CPK32 is an ABA signaling component that regulates the ABA-responsive gene expression via ABF4.
Title: Arabidopsis calcium-dependent protein kinase AtCPK32 interacts with ABF4, a transcriptional regulator of abscisic acid-responsive gene expression, and modulates its activity.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001161154.1

Supported by ESTs:

NM_001203005.2

Supported by ESTs:

NM_001338390.1

Supported by ESTs:

NM_001338391.1

Supported by ESTs:

NM_112816.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables DNA-binding transcription factor activity	TAS Traceable Author Statement more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within abscisic acid-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within glucosinolate metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of chlorophyll catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of leaf senescence	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within response to abscisic acid	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to salt stress	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to water deprivation	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: ABRE binding factor 4

NP_001154626.1

ABRE binding factor 4 (ABF4); CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827); BEST Arabidopsis thaliana protein match is: abscisic acid responsive element-binding factor 1 (TAIR:AT1G49720.2); Has 1216 Blast hits to 1060 proteins in 118 species: Archae - 0; Bacteria - 4; Metazoa - 293; Fungi - 83; Plants - 609; Viruses - 0; Other Eukaryotes - 227 (source: NCBI BLink).

NP_001189934.1

ABRE binding factor 4 (ABF4); CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: abscisic acid responsive element-binding factor 1 (TAIR:AT1G49720.1).

NP_566629.1

ABRE binding factor 4 (ABF4); FUNCTIONS IN: protein binding, DNA binding, transcription activator activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: abscisic acid responsive element-binding factor 1 (TAIR:AT1G49720.1); Has 5268 Blast hits to 4676 proteins in 263 species: Archae - 0; Bacteria - 14; Metazoa - 1616; Fungi - 400; Plants - 1635; Viruses - 0; Other Eukaryotes - 1603 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

6687042..6690123

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001203005.2 → NP_001189934.1 ABRE binding factor 4 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001189934.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V7Z7, F4JB53

Conserved Domains (2) summary

cd14707
Location:353 → 400

bZIP_plant_BZIP46; Basic leucine zipper (bZIP) domain of uncharaterized Plant BZIP transcription factors: a DNA-binding and dimerization domain

cl12013
Location:260 → 399

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
NM_112816.3 → NP_566629.1 ABRE binding factor 4 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_566629.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LT88, Q9M7Q2

UniProtKB/TrEMBL

A0A178V7Z7

Conserved Domains (2) summary

cd14707
Location:353 → 400

bZIP_plant_BZIP46; Basic leucine zipper (bZIP) domain of uncharaterized Plant BZIP transcription factors: a DNA-binding and dimerization domain

cl12013
Location:260 → 399

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
NM_001338390.1 → NP_001326148.1 ABRE binding factor 4 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V9K6, A0A1I9LNE0
NM_001161154.1 → NP_001154626.1 ABRE binding factor 4 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001154626.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V9K6, F4JB55

Conserved Domains (1) summary

cd14707
Location:353 → 407

bZIP_plant_BZIP46; Basic leucine zipper (bZIP) domain of uncharaterized Plant BZIP transcription factors: a DNA-binding and dimerization domain
NM_001338391.1 → NP_001326147.1 ABRE binding factor 4 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LT88, Q9M7Q2

UniProtKB/TrEMBL

A0A178V7Z7