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    AMSH1 associated molecule with the SH3 domain of STAM 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841301, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AMSH1
    Official Full Name
    associated molecule with the SH3 domain of STAM 1
    Primary source
    TAIR:AT1G48790
    Locus tag
    AT1G48790
    See related
    Araport:AT1G48790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    associated molecule with the SH3 domain of STAM 1; F11I4.4; F11I4_4
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    Genomic context

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    See AMSH1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Sequence:
    Chromosome: 1; NC_003070.9 (18043672..18047806, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene delta-adaptin Neighboring gene hypothetical protein (DUF1639) Neighboring gene uncharacterized protein Neighboring gene Terpenoid cyclases/Protein prenyltransferases superfamily protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The deubiquitinating enzyme AMSH1 is required for rhizobial infection and nodule organogenesis in Lotus japonicus. Małolepszy A, et al. Plant J, 2015 Aug. PMID 26119469
    2. Arabidopsis ALIX is required for the endosomal localization of the deubiquitinating enzyme AMSH3. Kalinowska K, et al. Proc Natl Acad Sci U S A, 2015 Oct 6. PMID 26324913, Free PMC Article
    3. The deubiquitinating enzyme AMSH1 and the ESCRT-III subunit VPS2.1 are required for autophagic degradation in Arabidopsis. Katsiarimpa A, et al. Plant Cell, 2013 Jun. PMID 23800962, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_103774.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables K63-linked deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal-dependent deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein K48-linked deubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein K63-linked deubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    associated molecule with the SH3 domain of STAM 1
    NP_564533.1
    • associated molecule with the SH3 domain of STAM 1 (AMSH1); CONTAINS InterPro DOMAIN/s: Mov34/MPN/PAD-1 (InterPro:IPR000555); BEST Arabidopsis thaliana protein match is: associated molecule with the SH3 domain of STAM 3 (TAIR:AT4G16144.1); Has 1172 Blast hits to 1019 proteins in 227 species: Archae - 0; Bacteria - 0; Metazoa - 476; Fungi - 293; Plants - 278; Viruses - 0; Other Eukaryotes - 125 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      18043672..18047806 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103774.4 → NP_564533.1  associated molecule with the SH3 domain of STAM 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564533.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LFY1, Q8VYB5, Q9C747
      UniProtKB/TrEMBL
      A0A178W2J9, A0A5S9WMT9
      Conserved Domains (2) summary
      cd08066
      Location:333 → 507
      MPN_AMSH_like; Mov34/MPN/PAD-1 family
      pfam08969
      Location:1 → 104
      USP8_dimer; USP8 dimerization domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VYB5.1

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