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    GroES-like zinc-binding alcohol dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836482, updated on 18-Sep-2024

    Summary

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    Official Full Name
    GroES-like zinc-binding alcohol dehydrogenase family protein
    Primary source
    TAIR:AT5G63620
    Locus tag
    AT5G63620
    See related
    Araport:AT5G63620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MBK5.9; MBK5_9
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (25466128..25468550, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene flavonol synthase 5 Neighboring gene cyclin-dependent kinase E;1 Neighboring gene uncharacterized protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Forward genetic screens identify a role for the mitochondrial HER2 in E-2-hexenal responsiveness. Scala A, et al. Plant Mol Biol, 2017 Nov. PMID 28918565, Free PMC Article
    2. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. HER2 is involved in transducing the perception of E-2-hexenal, which changes the redox status of the mitochondria.
      Title: Forward genetic screens identify a role for the mitochondrial HER2 in E-2-hexenal responsiveness.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001345597.1
    NM_125757.2
    NM_180926.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cobalt ion binding HDA PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding HDA PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to alcohol IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    GroES-like zinc-binding alcohol dehydrogenase family protein
    NP_568975.2
    • GroES-like zinc-binding alcohol dehydrogenase family protein; FUNCTIONS IN: cobalt ion binding, zinc ion binding; INVOLVED IN: oxidation reduction; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GroES-like (InterPro:IPR011032), Alcohol dehydrogenase GroES-like (InterPro:IPR013154), Alcohol dehydrogenase, C-terminal (InterPro:IPR013149), Alcohol dehydrogenase superfamily, zinc-containing (InterPro:IPR002085); BEST Arabidopsis thaliana protein match is: GroES-like zinc-binding dehydrogenase family protein (TAIR:AT1G64710.1); Has 51156 Blast hits to 51010 proteins in 3327 species: Archae - 886; Bacteria - 33078; Metazoa - 1881; Fungi - 3909; Plants - 3940; Viruses - 3; Other Eukaryotes - 7459 (source: NCBI BLink).
    NP_851257.1
    • GroES-like zinc-binding alcohol dehydrogenase family protein; FUNCTIONS IN: cobalt ion binding, zinc ion binding; INVOLVED IN: oxidation reduction; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GroES-like (InterPro:IPR011032), Alcohol dehydrogenase GroES-like (InterPro:IPR013154), Alcohol dehydrogenase, C-terminal (InterPro:IPR013149), Alcohol dehydrogenase superfamily, zinc-containing (InterPro:IPR002085); BEST Arabidopsis thaliana protein match is: GroES-like zinc-binding dehydrogenase family protein (TAIR:AT1G64710.1); Has 51624 Blast hits to 51478 proteins in 3352 species: Archae - 890; Bacteria - 33556; Metazoa - 1876; Fungi - 3906; Plants - 3943; Viruses - 3; Other Eukaryotes - 7450 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25466128..25468550 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180926.3 → NP_851257.1  GroES-like zinc-binding alcohol dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851257.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UMZ8, A0A5S9YHW6, Q8LDF7, Q93ZM6
      Conserved Domains (1) summary
      cd08263
      Location:56 → 425
      Zn_ADH10; Alcohol dehydrogenases of the MDR family

    2. NM_001345597.1 → NP_001331700.1  GroES-like zinc-binding alcohol dehydrogenase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BEP1

    3. NM_125757.2 → NP_568975.2  GroES-like zinc-binding alcohol dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568975.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9YHW6, F4KAS6, Q8LDF7
      Conserved Domains (2) summary
      cd08263
      Location:56 → 425
      Zn_ADH10; Alcohol dehydrogenases of the MDR family
      COG1062
      Location:56 → 426
      FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version

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