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    Zfp41 zinc finger protein 41 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100910508, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp41provided by RGD
    Official Full Name
    zinc finger protein 41provided by RGD
    Primary source
    RGD:1307587
    See related
    EnsemblRapid:ENSRNOG00000007489 AllianceGenome:RGD:1307587
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307587
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZFP41 (ZFP41 zinc finger protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 50.0), Spleen (RPKM 48.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp41 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (109188010..109198546)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (107307303..107320164)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (116653618..116665414)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene lymphocyte antigen 6 family member H Neighboring gene glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Neighboring gene GLI family zinc finger 4 Neighboring gene DNA topoisomerase I mitochondrial

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 41 homolog
    Names
    GLI-Kruppel family member GLI4 (oncogene HKR4)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      109188010..109198546
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008765625.4 → XP_008763847.1  zinc finger protein 41 homolog

      See identical proteins and their annotated locations for XP_008763847.1

      UniProtKB/TrEMBL
      D3ZZK5
      Related
      ENSRNOP00000089045.1, ENSRNOT00000104546.2
      Conserved Domains (2) summary
      COG5189
      Location:111 → 191
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:117 → 137
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_039080529.2 → XP_038936457.1  zinc finger protein 41 homolog

      UniProtKB/TrEMBL
      D3ZZK5
      Related
      ENSRNOP00000068439.1, ENSRNOT00000076606.3
      Conserved Domains (2) summary
      COG5189
      Location:111 → 191
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:117 → 137
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_008765626.4 → XP_008763848.1  zinc finger protein 41 homolog

      See identical proteins and their annotated locations for XP_008763848.1

      UniProtKB/TrEMBL
      D3ZZK5
      Related
      ENSRNOP00000097386.1, ENSRNOT00000107500.2
      Conserved Domains (2) summary
      COG5189
      Location:111 → 191
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:117 → 137
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_063264671.1 → XP_063120741.1  zinc finger protein 41 homolog

      UniProtKB/TrEMBL
      D3ZZK5

    5. XM_039080530.2 → XP_038936458.1  zinc finger protein 41 homolog

      UniProtKB/TrEMBL
      D3ZZK5
      Related
      ENSRNOP00000099994.1, ENSRNOT00000172546.1
      Conserved Domains (2) summary
      COG5189
      Location:111 → 191
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:117 → 137
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials