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    Wscd1 WSC domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287466, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Wscd1provided by RGD
    Official Full Name
    WSC domain containing 1provided by RGD
    Primary source
    RGD:1308212
    See related
    EnsemblRapid:ENSRNOG00000007869 AllianceGenome:RGD:1308212
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308212
    Summary
    Predicted to enable sulfotransferase activity. Predicted to be located in Golgi membrane. Orthologous to human WSCD1 (WSC domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 268.5), Kidney (RPKM 48.3) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Wscd1 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (56884404..56924013)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (56385858..56426442)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (58330711..58372966)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102547395 Neighboring gene uncharacterized LOC102547579 Neighboring gene uncharacterized LOC120095135 Neighboring gene uncharacterized LOC120095327

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC105510

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables sulfotransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    sialate:O-sulfotransferase 1
    Names
    WSC domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024234.2 → NP_001019405.1  sialate:O-sulfotransferase 1

      See identical proteins and their annotated locations for NP_001019405.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      Q505J3
      UniProtKB/TrEMBL
      A6HGC8
      Conserved Domains (2) summary
      smart00321
      Location:139 → 231
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl21551
      Location:422 → 551
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      56884404..56924013
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017597102.3 → XP_017452591.1  sialate:O-sulfotransferase 1 isoform X1

      UniProtKB/Swiss-Prot
      Q505J3
      UniProtKB/TrEMBL
      A6HGC8
      Related
      ENSRNOP00000010358.4, ENSRNOT00000010358.8
      Conserved Domains (2) summary
      smart00321
      Location:139 → 231
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl21551
      Location:422 → 551
      Sulfotransfer_1; Sulfotransferase domain

    2. XM_017597106.3 → XP_017452595.1  sialate:O-sulfotransferase 1 isoform X1

      UniProtKB/Swiss-Prot
      Q505J3
      UniProtKB/TrEMBL
      A6HGC8
      Conserved Domains (2) summary
      smart00321
      Location:139 → 231
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl21551
      Location:422 → 551
      Sulfotransfer_1; Sulfotransferase domain

    3. XM_063268666.1 → XP_063124736.1  sialate:O-sulfotransferase 1 isoform X1

      UniProtKB/Swiss-Prot
      Q505J3
      UniProtKB/TrEMBL
      A6HGC8

    4. XM_017597104.3 → XP_017452593.1  sialate:O-sulfotransferase 1 isoform X1

      UniProtKB/Swiss-Prot
      Q505J3
      UniProtKB/TrEMBL
      A6HGC8
      Conserved Domains (2) summary
      smart00321
      Location:139 → 231
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl21551
      Location:422 → 551
      Sulfotransfer_1; Sulfotransferase domain

    5. XM_017597103.3 → XP_017452592.1  sialate:O-sulfotransferase 1 isoform X1

      UniProtKB/Swiss-Prot
      Q505J3
      UniProtKB/TrEMBL
      A6HGC8
      Conserved Domains (2) summary
      smart00321
      Location:139 → 231
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl21551
      Location:422 → 551
      Sulfotransfer_1; Sulfotransferase domain

    6. XM_063268667.1 → XP_063124737.1  sialate:O-sulfotransferase 1 isoform X1

      UniProtKB/Swiss-Prot
      Q505J3
      UniProtKB/TrEMBL
      A6HGC8

    7. XM_017597105.3 → XP_017452594.1  sialate:O-sulfotransferase 1 isoform X1

      UniProtKB/Swiss-Prot
      Q505J3
      UniProtKB/TrEMBL
      A6HGC8
      Conserved Domains (2) summary
      smart00321
      Location:139 → 231
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl21551
      Location:422 → 551
      Sulfotransfer_1; Sulfotransferase domain

    8. XM_017597108.3 → XP_017452597.1  sialate:O-sulfotransferase 1 isoform X1

      UniProtKB/Swiss-Prot
      Q505J3
      UniProtKB/TrEMBL
      A6HGC8
      Conserved Domains (2) summary
      smart00321
      Location:139 → 231
      WSC; present in yeast cell wall integrity and stress response component proteins
      cl21551
      Location:422 → 551
      Sulfotransfer_1; Sulfotransferase domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q505J3.1 GenPept UniProtKB/Swiss-Prot:Q505J3

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