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    Rcan3 RCAN family member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362627, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rcan3provided by RGD
    Official Full Name
    RCAN family member 3provided by RGD
    Primary source
    RGD:1311826
    See related
    EnsemblRapid:ENSRNOG00000018576 AllianceGenome:RGD:1311826
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Dscr1l2
    Summary
    Predicted to enable calcium-dependent protein serine/threonine phosphatase regulator activity; phosphatase binding activity; and troponin I binding activity. Predicted to be involved in calcium-mediated signaling. Predicted to be active in cytoplasm and nucleus. Orthologous to human RCAN3 (RCAN family member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 59.6), Lung (RPKM 53.0) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rcan3 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (152934561..152955502, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (147650935..147671881, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (153773461..153790271, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103007 Neighboring gene serine and arginine repetitive matrix 1 Neighboring gene noncompact myelin associated protein Neighboring gene uncharacterized LOC134487010 Neighboring gene NIPA-like domain containing 3 Neighboring gene sperm-tail PG-rich repeat containing 1 Neighboring gene microRNA 6333 Neighboring gene small nucleolar RNA SNORD104 Neighboring gene grainyhead-like transcription factor 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium-dependent protein serine/threonine phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables troponin I binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in calcium-mediated signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    calcipressin-3
    Names
    Down syndrome critical region gene 1-like 2
    regulator of calcineurin 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012746.1NP_001012764.1  calcipressin-3

      See identical proteins and their annotated locations for NP_001012764.1

      Status: PROVISIONAL

      Source sequence(s)
      AY919305
      UniProtKB/TrEMBL
      Q5D1N7
      Related
      ENSRNOP00000089043.2, ENSRNOT00000113528.2
      Conserved Domains (1) summary
      pfam04847
      Location:83242
      Calcipressin; Calcipressin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      152934561..152955502 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006239218.5XP_006239280.1  calcipressin-3 isoform X1

      See identical proteins and their annotated locations for XP_006239280.1

      UniProtKB/TrEMBL
      A6IT55, F7ENE7
      Conserved Domains (1) summary
      pfam04847
      Location:58225
      Calcipressin
    2. XM_039110406.2XP_038966334.1  calcipressin-3 isoform X1

      UniProtKB/TrEMBL
      A6IT55, F7ENE7
      Conserved Domains (1) summary
      pfam04847
      Location:58225
      Calcipressin
    3. XM_039110405.2XP_038966333.1  calcipressin-3 isoform X1

      UniProtKB/TrEMBL
      A6IT55, F7ENE7
      Conserved Domains (1) summary
      pfam04847
      Location:58225
      Calcipressin