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    NIFK-AS1 NIFK antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 254128, updated on 10-Dec-2024

    Summary

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    Official Symbol
    NIFK-AS1provided by HGNC
    Official Full Name
    NIFK antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:27385
    See related
    Ensembl:ENSG00000236859 AllianceGenome:HGNC:27385
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in appendix (RPKM 4.8), lymph node (RPKM 4.7) and 25 other tissues See more
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    Genomic context

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    See NIFK-AS1 in Genome Data Viewer
    Location:
    2q14.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (121649654..121728560)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (122084934..122163835)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (122407230..122486136)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:122091915-122092848 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:122094177-122094762 Neighboring gene ribosomal protein S17 pseudogene 7 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:122109698-122109870 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16463 Neighboring gene cytoplasmic linker associated protein 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:122140378-122140878 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:122187059-122188258 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:122205649-122205872 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16464 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11922 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16465 Neighboring gene CLASP1 antisense RNA 1 Neighboring gene RNA, U4atac small nuclear Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16466 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16467 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16468 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:122406621-122407247 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:122405992-122406620 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16469 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:122437634-122438136 Neighboring gene ribosomal protein L12 pseudogene 15 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16470 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:122457551-122458050 Neighboring gene uncharacterized LOC124906186 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16471 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11923 Neighboring gene nucleophosmin 1 pseudogene 32 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16472 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:122533206-122534180 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:122534181-122535155 Neighboring gene uncharacterized LOC105373590 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:122547721-122548382 Neighboring gene nucleolar protein interacting with the FHA domain of MKI67 Neighboring gene translin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Long non-coding RNA NIFK-AS1 inhibits M2 polarization of macrophages in endometrial cancer through targeting miR-146a. Zhou YX, et al. Int J Biochem Cell Biol, 2018 Nov. PMID 30176290
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NIFK-AS1 inhibits M2 polarization of macrophages in endometrial cancer through targeting miR-146a
      Title: Long non-coding RNA NIFK-AS1 inhibits M2 polarization of macrophages in endometrial cancer through targeting miR-146a.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Clone Names

    • AC018737.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_037856.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longest transcript.
      Source sequence(s)
      BC047384
      Related
      ENST00000439321.1

    2. NR_037857.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an internal segment in the 5' region and has an alternate and shorter 3' sequence, as compared to variant 1.
      Source sequence(s)
      AC018737, AK098264

    3. NR_037858.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate and shorter 3' sequence, as compared to variant 1.
      Source sequence(s)
      AC018737, BC036624
      Related
      ENST00000670491.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      121649654..121728560
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      122084934..122163835
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials