Rap2l Ras-associated protein 2-like [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Rap2lprovided by FlyBase
Official Full Name: Ras-associated protein 2-likeprovided by FlyBase
Primary source: FLYBASE:FBgn0283666
Locus tag: Dmel_CG3204
See related: AllianceGenome:FB:FBgn0283666
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG3204; Dm Rap21; Dmel\CG3204; l(2)SH0581; l(2)SH2 0581; O96692; Rap2; Rap21; Rap2L
Summary: Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in germ-line stem cell population maintenance. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head and adult heart. Orthologous to several human genes including RAP2C (RAP2C, member of RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (24063051..24065405)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (19950574..19952928)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables GDP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GDP binding	ISS Inferred from Sequence or Structural Similarity more info
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTP binding	ISS Inferred from Sequence or Structural Similarity more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables GTPase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in Rap protein signal transduction	IBA Inferred from Biological aspect of Ancestor more info
involved_in Rap protein signal transduction	IEA Inferred from Electronic Annotation more info
involved_in Rap protein signal transduction	ISS Inferred from Sequence or Structural Similarity more info
involved_in germ-line stem cell population maintenance	IGI Inferred from Genetic Interaction more info	PubMed
involved_in negative regulation of cell migration	IBA Inferred from Biological aspect of Ancestor more info
involved_in signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

Names: CG3204-PA; CG3204-PC; CG3204-PD; Rap2l-PA; Rap2l-PC; Rap2l-PD; lethal (2) SH0581

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The following sections contain reference sequences that belong to a specific genome build. Explain