UQCR-14L Ubiquinol-cytochrome c reductase 14 kDa subunit-like [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: UQCR-14Lprovided by FlyBase
Official Full Name: Ubiquinol-cytochrome c reductase 14 kDa subunit-likeprovided by FlyBase
Primary source: FLYBASE:FBgn0039576
Locus tag: Dmel_CG17856
See related: AllianceGenome:FB:FBgn0039576
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG17856; Dmel\CG17856; UCR6
Summary: Involved in determination of adult lifespan; mitochondrial respiratory chain complex III assembly; and response to reactive oxygen species. Predicted to be part of respiratory chain complex III. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in inherited metabolic disorder and mitochondrial complex III deficiency nuclear type 3. Orthologous to human UQCRB (ubiquinol-cytochrome c reductase binding protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (28294048..28294550)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (24119770..24120272)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in determination of adult lifespan	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial electron transport, ubiquinol to cytochrome c	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial electron transport, ubiquinol to cytochrome c	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial electron transport, ubiquinol to cytochrome c	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial respiratory chain complex III assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to reactive oxygen species	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
part_of respiratory chain complex III	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex III	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex III	ISS Inferred from Sequence or Structural Similarity more info

Names: CG17856-PA; UQCR-14L-PA; Ubiquinol-cytochrome C reductase complex 14 kDa protein; Ubiquinol-cytochrome c reductase 14 kDa protein; complex III

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The following sections contain reference sequences that belong to a specific genome build. Explain