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    Actn3 alpha actinin 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44964, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Actn3provided by FlyBase
    Official Full Name
    alpha actinin 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0015008
    Locus tag
    Dmel_CG8953
    See related
    AllianceGenome:FB:FBgn0015008
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    acta-3; actn3; CG8953; dabp; Dmel\CG8953; ORF1
    Orthologs
    all
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    Genomic context

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    See Actn3 in Genome Data Viewer
    Location:
    89E5-89E5; 3-59 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16975885..16977795, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (12801607..12803517, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Abdominal B Neighboring gene long non-coding RNA:CR46267 Neighboring gene Vacuolar H[+] ATPase M9.7 subunit d Neighboring gene Adenosylhomocysteinase like 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mathematical model to predict regions of chromatin attachment to the nuclear matrix. Singh GB, et al. Nucleic Acids Res, 1997 Apr 1. PMID 9060438, Free PMC Article
    2. The bithorax complex of Drosophila melanogaster: Underreplication and morphology in polytene chromosomes. Moshkin YM, et al. Proc Natl Acad Sci U S A, 2001 Jan 16. PMID 11136231, Free PMC Article
    3. Complete sequence of the bithorax complex of Drosophila. Martin CH, et al. Proc Natl Acad Sci U S A, 1995 Aug 29. PMID 7667301, Free PMC Article
    4. Misato underlies visceral myopathy in Drosophila. Min S, et al. Sci Rep, 2017 Dec 18. PMID 29255146, Free PMC Article
    5. Prominent actin fiber arrays in Drosophila tendon cells represent architectural elements different from stress fibers. Alves-Silva J, et al. Mol Biol Cell, 2008 Oct. PMID 18667532, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    alpha actinin 3
    Names
    Actn3-PA
    CG8953-PA
    actinin 3
    alpha-actinin-like
    alpha-actinin3
    open reading frame 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      16975885..16977795 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080062.2 → NP_524801.1  alpha actinin 3 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524801.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V409, Q9VEQ5
      Related
      FBpp0082822
      Conserved Domains (1) summary
      cd00014
      Location:449 → 546
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q24109 Q24109
    Q9VEQ5 Q9VEQ5

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