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    CG9588 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41672, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG9588provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038166
    Locus tag
    Dmel_CG9588
    See related
    AllianceGenome:FB:FBgn0038166
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    9588; Dmel\CG9588; dp27; p27
    Summary
    Predicted to be involved in proteasome regulatory particle assembly. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including CNS glial cell; central brain primordium; embryonic/larval midgut primordium; ganglia; and mesoderm. Orthologous to human PSMD9 (proteasome 26S subunit, non-ATPase 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9588 in Genome Data Viewer
    Location:
    87F7-87F7; 3-54 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13675092..13676681, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9500814..9502403, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene B52 Neighboring gene TWIK-related acid-sensitive K[+] channel 6 Neighboring gene Lkb1 kinase Neighboring gene oocyte maintenance defects Neighboring gene falafel Neighboring gene uncharacterized protein Neighboring gene flyers-cup

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Accurate gene-tree reconstruction by learning gene- and species-specific substitution rates across multiple complete genomes. Rasmussen MD, et al. Genome Res, 2007 Dec. PMID 17989260, Free PMC Article
    2. The Drosophila Lkb1 kinase is required for spindle formation and asymmetric neuroblast division. Bonaccorsi S, et al. Development, 2007 Jun. PMID 17507418
    3. Proteasome regulation by ADP-ribosylation. Cho-Park PF, et al. Cell, 2013 Apr 25. PMID 23622245, Free PMC Article
    4. A Drosophila model of diabetic neuropathy reveals a role of proteasome activity in the glia. Suzuki M, et al. iScience, 2023 Jun 16. PMID 37378316, Free PMC Article
    5. On the role of PDZ domain-encoding genes in Drosophila border cell migration. Aranjuez G, et al. G3 (Bethesda), 2012 Nov. PMID 23173089, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in proteasome regulatory particle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteasome regulatory particle assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9588-PA
    NP_650301.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      13675092..13676681 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142044.4 → NP_650301.1  uncharacterized protein Dmel_CG9588 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650301.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VFS8
      Related
      FBpp0082314
      Conserved Domains (1) summary
      cd00136
      Location:116 → 186
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VFS8.1 Q9VFS8

    Gene LinkOut

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