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    CG11964 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41068, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11964provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037644
    Locus tag
    Dmel_CG11964
    See related
    AllianceGenome:FB:FBgn0037644
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11964
    Summary
    Predicted to be involved in regulation of apoptotic process. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is expressed in organism and spermatozoon. Human ortholog(s) of this gene implicated in colorectal cancer; morbid obesity; and primary immunodeficiency disease. Orthologous to human CTNNBL1 (catenin beta like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11964 in Genome Data Viewer
    Location:
    85B7-85B7; 3-48 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8942954..8945020, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4768676..4770742, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44020 Neighboring gene long non-coding RNA:osk Neighboring gene oskar Neighboring gene Succinyl-coenzyme A synthetase beta subunit, ADP-forming Neighboring gene ichor Neighboring gene Carbonic anhydrase beta Neighboring gene Ras-related GTP binding A/B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. BREs mediate both repression and activation of oskar mRNA translation and act in trans. Reveal B, et al. Dev Cell, 2010 Mar 16. PMID 20230756, Free PMC Article
    2. The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster. Jin W, et al. Nat Genet, 2001 Dec. PMID 11726925
    3. E(var)3-9 of Drosophila melanogaster encodes a zinc finger protein. Weiler KS. Genetics, 2007 Sep. PMID 17660546, Free PMC Article
    4. Expression-Based Cell Lineage Analysis in Drosophila Through a Course-Based Research Experience for Early Undergraduates. Olson JM, et al. G3 (Bethesda), 2019 Nov 5. PMID 31690598, Free PMC Article
    5. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11964-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8942954..8945020 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141590.4 → NP_649847.1  uncharacterized protein Dmel_CG11964 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649847.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHJ7
      Related
      FBpp0081493
      Conserved Domains (2) summary
      cd00020
      Location:155 → 251
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam08216
      Location:87 → 183
      CTNNBL; Catenin-beta-like, Arm-motif containing nuclear
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHJ7 Q9VHJ7

    Gene LinkOut

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