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    Gasp gasp [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40745, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Gaspprovided by FlyBase
    Official Full Name
    gaspprovided by FlyBase
    Primary source
    FLYBASE:FBgn0026077
    Locus tag
    Dmel_CG10287
    See related
    AllianceGenome:FB:FBgn0026077
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    2A12; anon-EST:ParkEST180; CG10287; Dmel\CG10287; gammaBert27; gasp; mAB 2A12; obst-C
    Summary
    Predicted to enable chitin binding activity. Involved in chitin-based cuticle development and regulation of tube size, open tracheal system. Located in chitin-based extracellular matrix. Is expressed in several structures, including Malpighian tubule primordium; adult fat body; anlage in statu nascendi; central brain anlage in statu nascendi; and epithelial tube. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Gasp in Genome Data Viewer
    Location:
    83D4-83D4; 3-47.5 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6088799..6100887, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1914521..1926609, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 83c Neighboring gene long non-coding RNA:CR44929 Neighboring gene Odorant-binding protein 83cd Neighboring gene Odorant-binding protein 83ef

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Control of airway tube diameter and integrity by secreted chitin-binding proteins in Drosophila. Tiklová K, et al. PLoS One, 2013. PMID 23826295, Free PMC Article
    2. A peritrophin-like protein expressed in the embryonic tracheae of Drosophila melanogaster. Barry MK, et al. Insect Biochem Mol Biol, 1999 Apr. PMID 10333571
    3. Learning sparse representations for fruit-fly gene expression pattern image annotation and retrieval. Yuan L, et al. BMC Bioinformatics, 2012 May 23. PMID 22621237, Free PMC Article
    4. Shaping of biological tubes by mechanical interaction of cell and extracellular matrix. Dong B, et al. Curr Opin Genet Dev, 2015 Jun. PMID 25819978
    5. Association of tracheal placodes with leg primordia in Drosophila and implications for the origin of insect tracheal systems. Franch-Marro X, et al. Development, 2006 Mar. PMID 16469971

    See all (56) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chitin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of tube size, open tracheal system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chitin-based extracellular matrix IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    gasp
    Names
    CG10287-PA
    CG10287-PB
    Gasp-PA
    Gasp-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6088799..6100887 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001104224.2 → NP_001097694.1  gasp, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097694.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JQU3, O97377
      Conserved Domains (2) summary
      smart00494
      Location:21 → 72
      ChtBD2; Chitin-binding domain type 2
      pfam01607
      Location:97 → 144
      CBM_14; Chitin binding Peritrophin-A domain

    2. NM_141354.3 → NP_649611.2  gasp, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649611.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O97377, Q9VNL0
      Related
      FBpp0078268
      Conserved Domains (2) summary
      smart00494
      Location:21 → 72
      ChtBD2; Chitin-binding domain type 2
      pfam01607
      Location:97 → 144
      CBM_14; Chitin binding Peritrophin-A domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8JQU3 A8JQU3
    O97377 O97377
    Q9VNL0 Q9VNL0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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