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    jdp jdp [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43630, updated on 17-Dec-2024

    Summary

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    Official Symbol
    jdpprovided by FlyBase
    Official Full Name
    jdpprovided by FlyBase
    Primary source
    FLYBASE:FBgn0027654
    Locus tag
    Dmel_CG2239
    See related
    AllianceGenome:FB:FBgn0027654
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2239; dJDP; Dmel\CG2239; JDP; p25a
    Summary
    Predicted to enable protein-folding chaperone binding activity and unfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in adult head and embryonic/larval corpus allatum. Orthologous to human DNAJC12 (DnaJ heat shock protein family (Hsp40) member C12). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See jdp in Genome Data Viewer
    Location:
    99F7-99F7; 3-100 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30517059..30527037, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26342781..26352759, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45552 Neighboring gene long non-coding RNA:CR45553 Neighboring gene tropomodulin Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two novel DnaJ chaperone proteins CG5001 and P58IPK regulate the pathogenicity of Huntington's disease related aggregates. Deo A, et al. Sci Rep, 2024 Sep 6. PMID 39242711, Free PMC Article
    2. Structural analysis of phylogenetically conserved J domain protein gene. Hahn Y, et al. Biochim Biophys Acta, 1999 Oct 28. PMID 10542335
    3. Long-term but not short-term blockade of dopamine release in Drosophila impairs orientation during flight in a visual attention paradigm. Ye Y, et al. Eur J Neurosci, 2004 Aug. PMID 15305868
    4. Identification of a protein phosphorylated by cAMP-dependent protein kinase in drosophila brain. Inoue H, et al. Brain Res, 2000 Sep 1. PMID 10967311
    5. Characterization of JDP genes, an evolutionarily conserved J domain-only protein family, from human and moths. Lee J, et al. Biochim Biophys Acta, 2000 Apr 25. PMID 10760603

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-folding chaperone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables unfolded protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in chaperone cofactor-dependent protein refolding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    jdp
    Names
    CG2239-PA
    CG2239-PB
    CG2239-PC
    jdp-PA
    jdp-PB
    jdp-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30517059..30527037 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170501.2 → NP_733380.1  jdp, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733380.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H0RNN1
      Related
      FBpp0085044
      Conserved Domains (1) summary
      pfam00226
      Location:17 → 79
      DnaJ; DnaJ domain

    2. NM_143550.3 → NP_651807.1  jdp, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651807.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IMI1, Q9TVP3, Q9V3I7
      Related
      FBpp0085043
      Conserved Domains (1) summary
      pfam00226
      Location:17 → 79
      DnaJ; DnaJ domain

    3. NM_170502.2 → NP_733381.1  jdp, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733381.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9TVP3
      Related
      FBpp0085045
      Conserved Domains (1) summary
      pfam00226
      Location:17 → 79
      DnaJ; DnaJ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9TVP3.2 Q9TVP3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
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