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    BomS3 Bomanin Short 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50209, updated on 9-Dec-2024

    Summary

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    Official Symbol
    BomS3provided by FlyBase
    Official Full Name
    Bomanin Short 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0040736
    Locus tag
    Dmel_CG16844
    See related
    AllianceGenome:FB:FBgn0040736
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH58911; Bom3; CG16844; CT37419; DIM 3; DIM3; Dmel\CG16844; im3; IM3
    Summary
    Involved in antibacterial humoral response; defense response to Gram-positive bacterium; and response to mycotoxin. Located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See BomS3 in Genome Data Viewer
    Location:
    55C4-55C4; 2-85 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18387895..18388734)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14275400..14276239)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Bomanin Short 4 Neighboring gene Bomanin Bicipital 2 Neighboring gene Bomanin Short 2 Neighboring gene Bomanin Tailed 2 Neighboring gene Bomanin Short 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Daisho Peptides Mediate Drosophila Defense Against a Subset of Filamentous Fungi. Cohen LB, et al. Front Immunol, 2020. PMID 32038657, Free PMC Article
    2. A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium. Huang J, et al. Proc Natl Acad Sci U S A, 2023 Mar 21. PMID 36917667, Free PMC Article
    3. Chronic exposure to the star polycation (SPc) nanocarrier in the larval stage adversely impairs life history traits in Drosophila melanogaster. Yan S, et al. J Nanobiotechnology, 2022 Dec 8. PMID 36482441, Free PMC Article
    4. Similar effects of high-fructose and high-glucose feeding in a Drosophila model of obesity and diabetes. Musselman LP, et al. PLoS One, 2019. PMID 31091299, Free PMC Article
    5. The GCN2-ATF4 Signaling Pathway Induces 4E-BP to Bias Translation and Boost Antimicrobial Peptide Synthesis in Response to Bacterial Infection. Vasudevan D, et al. Cell Rep, 2017 Nov 21. PMID 29166596, Free PMC Article

    See all (89) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in antibacterial humoral response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in defense response to Gram-positive bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to bacterium HEP PubMed 
    involved_in response to mycotoxin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bomanin short 3
    Names
    BomS3-PA
    BomS3-PB
    CG16844-PA
    CG16844-PB
    bomanin 3
    bomanin S3
    immune induced molecule 3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18387895..18388734
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299640.1 → NP_001286569.1  bomanin short 3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286569.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V8G0
      UniProtKB/TrEMBL
      A0A0B4LGW9
      Conserved Domains (1) summary
      pfam08194
      Location:1 → 36
      DIM; DIM protein

    2. NM_144111.3 → NP_652368.1  bomanin short 3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652368.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9V8G0
      UniProtKB/TrEMBL
      A0A0B4LGW9
      Related
      FBpp0085846
      Conserved Domains (1) summary
      pfam08194
      Location:1 → 36
      DIM; DIM protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LGW9 A0A0B4LGW9
    Q8IGC3 Q8IGC3
    Q9V8G0.1 Q9V8G0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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