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    Rpp25l ribonuclease P/MRP 25 subunit-like [ Mus musculus (house mouse) ]

    Gene ID: 69961, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rpp25lprovided by MGI
    Official Full Name
    ribonuclease P/MRP 25 subunit-likeprovided by MGI
    Primary source
    MGI:MGI:1917211
    See related
    Ensembl:ENSMUSG00000036114 AllianceGenome:MGI:1917211
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rppl25; 2810432D09Rik
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in nucleus. Predicted to be part of ribonuclease MRP complex. Is expressed in cerebral cortex ventricular layer. Orthologous to human RPP25L (ribonuclease P/MRP subunit p25 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in colon adult (RPKM 15.9), adrenal adult (RPKM 15.3) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rpp25l in Genome Data Viewer
    Location:
    4 A5; 4 21.97 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (41712033..41713517, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (41712033..41713517, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12405 Neighboring gene ciliary neurotrophic factor receptor Neighboring gene STARR-seq mESC enhancer starr_10037 Neighboring gene STARR-positive B cell enhancer ABC_E11235 Neighboring gene dynactin 3 Neighboring gene AT-rich interaction domain 3C

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in tRNA 5'-leader removal IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonuclease MRP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ribonuclease P protein subunit p25-like protein
    Names
    RNase P protein subunit-like p25
    alba-like protein C9orf23 homolog
    rpp25-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027278.3NP_081554.2  ribonuclease P protein subunit p25-like protein

      See identical proteins and their annotated locations for NP_081554.2

      Status: VALIDATED

      Source sequence(s)
      AJ293897, BF146902
      Consensus CDS
      CCDS18068.1
      UniProtKB/Swiss-Prot
      Q99JH1, Q9CYX4
      Related
      ENSMUSP00000041477.4, ENSMUST00000038434.4
      Conserved Domains (1) summary
      pfam01918
      Location:2789
      Alba

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      41712033..41713517 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)