U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    DGCR5 DiGeorge syndrome critical region gene 5 [ Homo sapiens (human) ]

    Gene ID: 26220, updated on 10-Dec-2024

    Summary

    Official Symbol
    DGCR5provided by HGNC
    Official Full Name
    DiGeorge syndrome critical region gene 5provided by HGNC
    Primary source
    HGNC:HGNC:16757
    See related
    Ensembl:ENSG00000273032 MIM:618040; AllianceGenome:HGNC:16757
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RIP; DGCR9; DGS-A; DGS-B; DGCR10; LINC00037; POM121L5P; NCRNA00037
    Summary
    Biomarker of Huntington's disease. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in brain (RPKM 4.8), adrenal (RPKM 1.0) and 5 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See DGCR5 in Genome Data Viewer
    Location:
    22q11.21
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (18970468..19031242)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (19345862..19406582)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (18957981..19018755)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene proline dehydrogenase 1 Neighboring gene uncharacterized LOC122455341 Neighboring gene human-specific endogenous retroviral insert PRODH enhancer Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:18934751-18935496 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:18945292-18945809 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:18957062-18957893 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:18985578-18985746 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:19005353-19005854 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:19007165-19007664 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13451 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:19024185-19024805 Neighboring gene family with sequence similarity 246 member C (gene/pseudogene) Neighboring gene CA15 pseudogene 1 Neighboring gene DiGeorge syndrome critical region gene 2 Neighboring gene DiGeorge syndrome critical region gene 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    BioGRID CRISPR Screen Phenotypes (1 hit/3 screens)

    EBI GWAS Catalog

    Description
    An atlas of genetic influences on human blood metabolites.
    EBI GWAS Catalog
    Human metabolic individuality in biomedical and pharmaceutical research.
    EBI GWAS Catalog

    Pathways from PubChem

    Interactions

    General gene information

    Other Names

    • DiGeorge syndrome critical region gene 10 (non-protein coding)
    • DiGeorge syndrome critical region gene 5 (non-protein coding)
    • DiGeorge syndrome critical region gene 9 (non-protein coding)
    • DiGeorge syndrome gene A
    • DiGeorge syndrome gene B
    • Rac1 inactivated peptide
    • cadherin EGF LAG seven-pass G-type receptor 1 pseudogene
    • long intergenic non-protein coding RNA 37

    Clone Names

    • KIAA1647, MGC45713, AC000095.10, AC000095.11

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_002733.3 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AC007326
      Related
      ENST00000421572.2
    2. NR_024159.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC000095, AC007326
      Related
      ENST00000675978.1
    3. NR_026651.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC000095, AC007326
    4. NR_045121.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate internal exon, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AC007326
    5. NR_110533.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 3' exon structure, resulting in a shorter transcript, compared to variant 1.
      Source sequence(s)
      AC000095, AC007326
      Related
      ENST00000440005.6

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      18970468..19031242
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      19345862..19406582
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    External link. Please review our privacy policy.