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    Ugt305A1 UDP-glycosyltransferase family 305 member A1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 59217, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Ugt305A1provided by FlyBase
    Official Full Name
    UDP-glycosyltransferase family 305 member A1provided by FlyBase
    Primary source
    FLYBASE:FBgn0042179
    Locus tag
    Dmel_CG18869
    See related
    AllianceGenome:FB:FBgn0042179
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.104; anon-WO0153538.77; CG18869; Dmel\CG18869; Tes36
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head. Orthologous to several human genes including UGT2A1 (UDP glucuronosyltransferase family 2 member A1 complex locus); UGT2A2 (UDP glucuronosyltransferase family 2 member A2); and UGT2A3 (UDP glucuronosyltransferase family 2 member A3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ugt305A1 in Genome Data Viewer
    Location:
    64A5-64A5; 3-10 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4059770..4061923)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4059770..4061923)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Reduction in Cnn dots 5 Neighboring gene Dpy-30-like 2 Neighboring gene uncharacterized protein Neighboring gene disembodied Neighboring gene wishful thinking Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. wishful thinking encodes a BMP type II receptor that regulates synaptic growth in Drosophila. Aberle H, et al. Neuron, 2002 Feb 14. PMID 11856529
    2. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article
    3. Identification of Genes Involved in the Differentiation of R7y and R7p Photoreceptor Cells in Drosophila. Earl JB, et al. G3 (Bethesda), 2020 Nov 5. PMID 32972998, Free PMC Article
    4. Rapidly evolving genes of Drosophila: differing levels of selective pressure in testis, ovary, and head tissues between sibling species. Jagadeeshan S, et al. Mol Biol Evol, 2005 Sep. PMID 15917496
    5. Editor's Highlight: Genetic Targets of Acute Toluene Inhalation in Drosophila melanogaster. Bushnell PJ, et al. Toxicol Sci, 2017 Mar 1. PMID 28013218, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-glycosyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycosylation ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-glycosyltransferase family 305 member A1
    Names
    CG18869-PA
    CG18869-PB
    Ugt305A1-PA
    Ugt305A1-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4059770..4061923
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_144446.2 → NP_652703.1  UDP-glycosyltransferase family 305 member A1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652703.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3YMT0, Q9I7T3
      Related
      FBpp0073060
      Conserved Domains (1) summary
      cl10013
      Location:242 → 461
      Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...

    2. NM_001274465.1 → NP_001261394.1  UDP-glycosyltransferase family 305 member A1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261394.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3YMT0, Q9I7T3
      Conserved Domains (1) summary
      cl10013
      Location:242 → 461
      Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3YMT0 Q3YMT0
    Q8T0U7 Q8T0U7
    Q9I7T3 Q9I7T3

    Gene LinkOut

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