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    B3gntl1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 210004, updated on 9-Dec-2024

    Summary

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    Official Symbol
    B3gntl1provided by MGI
    Official Full Name
    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1provided by MGI
    Primary source
    MGI:MGI:2441705
    See related
    Ensembl:ENSMUSG00000046605 AllianceGenome:MGI:2441705
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    QTGAL; 6030413G23Rik
    Summary
    Predicted to enable tRNA-queuosine(34) galactosyltransferase activity. Predicted to be involved in regulation of translation and tRNA modification. Predicted to be active in cytoplasm. Orthologous to human B3GNTL1 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 3.9), limb E14.5 (RPKM 2.9) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See B3gntl1 in Genome Data Viewer
    Location:
    11 E2; 11 86.14 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (121507023..121563985, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (121616197..121673160, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr11:121312999-121313300 Neighboring gene fructosamine 3 kinase Neighboring gene tubulin-specific chaperone d Neighboring gene STARR-seq mESC enhancer starr_31381 Neighboring gene zinc finger protein 750 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:121420970-121421165 Neighboring gene STARR-seq mESC enhancer starr_31382 Neighboring gene predicted gene, 53659 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:121534171-121534280 Neighboring gene STARR-positive B cell enhancer mm9_chr11:121534352-121534653 Neighboring gene ribosomal protein, large, P0 pseudogene Neighboring gene meteorin, glial cell differentiation regulator-like Neighboring gene predicted gene 12589 Neighboring gene predicted gene, 30338

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
    2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC113804, MGC159329

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables tRNA-queuosine(34) galactosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables tRNA-queuosine(34) galactosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in regulation of translation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in tRNA modification ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in tRNA modification ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    queuosine-tRNA galactosyltransferase; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1
    Names
    BGnT-like protein 1
    beta1,3-N-acetylglucosaminyltransferase-like protein 1
    beta3Gn-T-like protein 1
    beta3GnTL1
    ortholog of human UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 B3GNTL1
    NP_848779.2
    XP_006532815.1
    XP_006532816.1
    XP_006532817.1
    XP_006532818.1
    XP_006532819.1
    XP_011247161.1
    XP_011247162.1
    XP_017169904.1
    XP_017169905.1
    XP_030101612.1
    XP_030101613.1
    XP_036012388.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178664.5 → NP_848779.2  queuosine-tRNA galactosyltransferase

      See identical proteins and their annotated locations for NP_848779.2

      Status: VALIDATED

      Source sequence(s)
      AK031361, BB641432, BC022739
      Consensus CDS
      CCDS25780.1
      UniProtKB/Swiss-Prot
      B7ZNC6, Q3U129, Q5HZJ4, Q8BLR1, Q8C0H0, Q8R1Y3
      Related
      ENSMUSP00000068590.8, ENSMUST00000067399.14
      Conserved Domains (1) summary
      cd06913
      Location:18 → 236
      beta3GnTL1_like; Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      121507023..121563985 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532753.5 → XP_006532816.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006532816.1

      Conserved Domains (1) summary
      cd06913
      Location:1 → 203
      beta3GnTL1_like; Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine

    2. XM_006532756.3 → XP_006532819.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X5

      See identical proteins and their annotated locations for XP_006532819.1

      Conserved Domains (1) summary
      cl11394
      Location:1 → 62
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    3. XM_006532754.5 → XP_006532817.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X3

      Conserved Domains (1) summary
      cl11394
      Location:9 → 134
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    4. XM_006532755.5 → XP_006532818.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X4

      See identical proteins and their annotated locations for XP_006532818.1

      Conserved Domains (1) summary
      cl11394
      Location:1 → 123
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    5. XM_036156495.1 → XP_036012388.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X3

      Conserved Domains (1) summary
      cl11394
      Location:9 → 134
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    6. XM_017314415.3 → XP_017169904.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X3

      Conserved Domains (1) summary
      cl11394
      Location:9 → 134
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    7. XM_006532752.4 → XP_006532815.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006532815.1

      UniProtKB/Swiss-Prot
      B7ZNC6, Q3U129, Q5HZJ4, Q8BLR1, Q8C0H0, Q8R1Y3
      Conserved Domains (1) summary
      cd06913
      Location:18 → 236
      beta3GnTL1_like; Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine

    8. XM_030245752.2 → XP_030101612.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X2

      Conserved Domains (1) summary
      cd06913
      Location:1 → 203
      beta3GnTL1_like; Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine

    9. XM_017314416.3 → XP_017169905.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X4

      Conserved Domains (1) summary
      cl11394
      Location:1 → 123
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    10. XM_011248859.4 → XP_011247161.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X4

      See identical proteins and their annotated locations for XP_011247161.1

      Conserved Domains (1) summary
      cl11394
      Location:1 → 123
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    11. XM_011248860.3 → XP_011247162.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X5

      See identical proteins and their annotated locations for XP_011247162.1

      Conserved Domains (1) summary
      cl11394
      Location:1 → 62
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

    12. XM_030245753.2 → XP_030101613.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X3

      Conserved Domains (1) summary
      cl11394
      Location:9 → 134
      Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3U129.1 GenPept UniProtKB/Swiss-Prot:Q3U129

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