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    HSPA1A heat shock protein family A (Hsp70) member 1A [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 720054, updated on 5-Mar-2024

    Summary

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    Gene symbol
    HSPA1A
    Gene description
    heat shock protein family A (Hsp70) member 1A
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    Hsp70; HSPA1B
    Orthologs
    human mouse all
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    Genomic context

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    See HSPA1A in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (137671024..137685835, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (32686352..32701250)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106997895 Neighboring gene small nucleolar RNA SNORD52 Neighboring gene small nucleolar RNA SNORD48 Neighboring gene heat shock 70 kDa protein 1 Neighboring gene heat shock protein family A (Hsp70) member 1 like Neighboring gene uncharacterized LOC106997897 Neighboring gene LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene valyl-tRNA synthetase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Form deprivation modulates retinal neurogenesis in primate experimental myopia. Tkatchenko AV, et al. Proc Natl Acad Sci U S A, 2006 Mar 21. PMID 16537371, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heat shock protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables misfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to unfolded protein IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chaperone cofactor-dependent protein refolding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein refolding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of mitotic spindle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in blood microparticle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    heat shock 70 kDa protein 1A
    Names
    heat shock 70 kDa protein 1A/1B
    heat shock 70kDa protein 1B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      137671024..137685835 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015136003.2 → XP_014991489.2  heat shock 70 kDa protein 1A

      UniProtKB/TrEMBL
      A0A5F8A2S3, A0A8J8XUA5, G7MRK7, H9Z8E3
      Conserved Domains (1) summary
      PTZ00009
      Location:1 → 611
      PTZ00009; heat shock 70 kDa protein; Provisional
    Nucleotide Protein
    Heading Accession and Version

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