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    ARHGAP25 Rho GTPase activating protein 25 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699828, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGAP25provided by VGNC
    Official Full Name
    Rho GTPase activating protein 25provided by VGNC
    Primary source
    VGNC:VGNC:69921
    Locus tag
    EGK_05398
    See related
    Ensembl:ENSMMUG00000015052
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP25 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (39974234..40065257, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (69769515..69860938)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein 10 Neighboring gene uncharacterized LOC114671947 Neighboring gene uncharacterized LOC114671946 Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 pseudogene Neighboring gene prokineticin receptor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in activation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phagocytosis, engulfment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in phagocytic cup IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266047.1 → NP_001252976.1  rho GTPase-activating protein 25

      See identical proteins and their annotated locations for NP_001252976.1

      Status: PROVISIONAL

      Source sequence(s)
      JU478090
      UniProtKB/TrEMBL
      A0A5F8A284, A0A5S6R939, A0A8J8XTU1, F6TL08, G7NA81
      Related
      ENSMMUP00000019729.4, ENSMMUT00000021099.4
      Conserved Domains (4) summary
      cd04390
      Location:156 → 354
      RhoGAP_ARHGAP22_24_25; RhoGAP_ARHGAP22_24_25: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been ...
      cd13263
      Location:45 → 157
      PH_RhoGap25-like; Rho GTPase activating protein 25 and related proteins Pleckstrin homology (PH) domain
      pfam00169
      Location:47 → 149
      PH; PH domain
      pfam13863
      Location:550 → 645
      DUF4200; Domain of unknown function (DUF4200)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      39974234..40065257 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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