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    SIRPA signal regulatory protein alpha [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717811, updated on 1-Aug-2024

    Summary

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    Gene symbol
    SIRPA
    Gene description
    signal regulatory protein alpha
    See related
    Ensembl:ENSMMUG00000018474
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SIRPA in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (64556084..64602710, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (34719679..34765854)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107000455 Neighboring gene serine/threonine kinase 35 Neighboring gene uncharacterized LOC107000450 Neighboring gene prodynorphin Neighboring gene tyrosine-protein phosphatase non-receptor type substrate 1-like Neighboring gene signal-regulatory protein beta-1-like Neighboring gene 60S ribosomal protein L29-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in positive regulation of T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of phagocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein phosphatase non-receptor type substrate 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      64556084..64602710 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015149397.2 → XP_015004883.2  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZE60, A0A5F7ZTA6
      Related
      ENSMMUP00000067395.1, ENSMMUT00000095219.1
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)

    2. XM_015149396.2 → XP_015004882.2  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1

      UniProtKB/TrEMBL
      G7N2S2
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)

    3. XM_028828274.1 → XP_028684107.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1

      UniProtKB/TrEMBL
      G7N2S2
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)

    4. XM_028828278.1 → XP_028684111.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZE60, A0A5F7ZTA6
      Related
      ENSMMUP00000062359.1, ENSMMUT00000109606.1
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)

    5. XM_028828276.1 → XP_028684109.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1

      UniProtKB/TrEMBL
      G7N2S2
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)

    6. XM_028828280.1 → XP_028684113.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZE60, A0A5F7ZTA6
      Related
      ENSMMUP00000063904.1, ENSMMUT00000079751.1
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)

    7. XM_028828277.1 → XP_028684110.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1

      UniProtKB/TrEMBL
      G7N2S2
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)

    8. XM_028828279.1 → XP_028684112.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZE60, A0A5F7ZTA6
      Related
      ENSMMUP00000068889.1, ENSMMUT00000092047.1
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)

    9. XM_028828275.1 → XP_028684108.1  tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1

      UniProtKB/TrEMBL
      G7N2S2
      Conserved Domains (3) summary
      cd05772
      Location:146 → 249
      IgC_SIRP_domain_2; Signal-regulatory protein (SIRP) immunoglobulin-like domain 2
      cd16085
      Location:251 → 354
      IgC_SIRP_domain_3; Signal-regulatory protein (SIRP) immunoglobulin-like domain 3
      cd16097
      Location:35 → 144
      IgV_SIRP; Immunoglobulin (Ig)-like domain of Signal-Regulatory Protein (SIRP)
    Nucleotide Protein
    Heading Accession and Version

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