U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ARHGEF10 Rho guanine nucleotide exchange factor 10 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 722745, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ARHGEF10provided by VGNC
    Official Full Name
    Rho guanine nucleotide exchange factor 10provided by VGNC
    Primary source
    VGNC:VGNC:83981
    See related
    Ensembl:ENSMMUG00000009472
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ARHGEF10 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (2330454..2471051)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (1572423..1719956)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999647 Neighboring gene uncharacterized LOC114680160 Neighboring gene uncharacterized LOC100423186 Neighboring gene kelch repeat and BTB domain containing 11 Neighboring gene uncharacterized LOC114680161

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic spindle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of stress fiber assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    rho guanine nucleotide exchange factor 10

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      2330454..2471051
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144687.2 → XP_015000173.2  rho guanine nucleotide exchange factor 10 isoform X3

      UniProtKB/TrEMBL
      A0A5F8ALD6, H9G288
      Related
      ENSMMUP00000078730.1, ENSMMUT00000101599.1
      Conserved Domains (2) summary
      cd00160
      Location:359 → 543
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl17171
      Location:576 → 640
      PH-like; Pleckstrin homology-like domain

    2. XM_028852314.1 → XP_028708147.1  rho guanine nucleotide exchange factor 10 isoform X2

      UniProtKB/TrEMBL
      H9G288
      Related
      ENSMMUP00000012393.4, ENSMMUT00000013222.4
      Conserved Domains (3) summary
      cd00160
      Location:397 → 581
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      PTZ00441
      Location:3 → 249
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      cl17171
      Location:614 → 678
      PH-like; Pleckstrin homology-like domain

    3. XM_015144683.2 → XP_015000169.2  rho guanine nucleotide exchange factor 10 isoform X1

      UniProtKB/TrEMBL
      A0A5F8A896, H9G288
      Related
      ENSMMUP00000053492.2, ENSMMUT00000061434.2
      Conserved Domains (2) summary
      cd00160
      Location:398 → 582
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl17171
      Location:615 → 679
      PH-like; Pleckstrin homology-like domain

    4. XM_028852315.1 → XP_028708148.1  rho guanine nucleotide exchange factor 10 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QDV6
      Conserved Domains (2) summary
      cd00160
      Location:232 → 416
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl17171
      Location:449 → 513
      PH-like; Pleckstrin homology-like domain

    5. XM_028852316.1 → XP_028708149.1  rho guanine nucleotide exchange factor 10 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QDV6
      Conserved Domains (2) summary
      cd00160
      Location:232 → 416
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cl17171
      Location:449 → 513
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.