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    KCND3 potassium voltage-gated channel subfamily D member 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 641437, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KCND3provided by VGNC
    Official Full Name
    potassium voltage-gated channel subfamily D member 3provided by VGNC
    Primary source
    VGNC:VGNC:106396
    Locus tag
    EGK_01095
    See related
    Ensembl:ENSMMUG00000050825
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KCND3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (112201928..112422419)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (112746510..112962280, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114678113 Neighboring gene uncharacterized LOC114671275 Neighboring gene DEAD-box helicase 20 Neighboring gene inka box actin regulator 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables A-type (transient outward) potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion export across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of voltage-gated potassium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A-type voltage-gated potassium channel KCND3; potassium voltage-gated channel subfamily D member 3
    Names
    potassium voltage-gated channel, Shal-related subfamily, member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001278467.2 → NP_001265396.1  A-type voltage-gated potassium channel KCND3 isoform 1

      See identical proteins and their annotated locations for NP_001265396.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      QNVO02000012
      UniProtKB/TrEMBL
      A0A5F7ZH27, A0A8J8YG89, F7GH76, H9FAY6
      Related
      ENSMMUP00000064475.1, ENSMMUT00000090803.1
      Conserved Domains (3) summary
      cd18419
      Location:6 → 143
      BTB_POZ_KCND3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily D member 3 (KCND3)
      pfam00520
      Location:186 → 412
      Ion_trans; Ion transport protein
      pfam11879
      Location:442 → 563
      DUF3399; Domain of unknown function (DUF3399)

    2. NM_001278468.2 → NP_001265397.1  A-type voltage-gated potassium channel KCND3 isoform 2

      See identical proteins and their annotated locations for NP_001265397.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 2 which lacks an internal segment and is shorter, compared to isoform 1.
      Source sequence(s)
      QNVO02000012
      UniProtKB/TrEMBL
      A0A5F8ACX1, H9FAY6
      Related
      ENSMMUP00000075720.1, ENSMMUT00000084389.1
      Conserved Domains (3) summary
      cd18419
      Location:6 → 143
      BTB_POZ_KCND3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily D member 3 (KCND3)
      pfam00520
      Location:186 → 412
      Ion_trans; Ion transport protein
      pfam11879
      Location:442 → 544
      DUF3399; Domain of unknown function (DUF3399)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      112201928..112422419
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015146696.2 → XP_015002182.1  potassium voltage-gated channel subfamily D member 3 isoform X1

      UniProtKB/TrEMBL
      A0A5F7ZH27, A0A8J8YG89, F7GH76, H9FAY6
      Conserved Domains (3) summary
      cd18419
      Location:6 → 143
      BTB_POZ_KCND3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily D member 3 (KCND3)
      pfam00520
      Location:186 → 412
      Ion_trans; Ion transport protein
      pfam11879
      Location:442 → 563
      DUF3399; Domain of unknown function (DUF3399)

    2. XM_015146712.2 → XP_015002198.1  potassium voltage-gated channel subfamily D member 3 isoform X2

      UniProtKB/TrEMBL
      A0A5F8ACX1, H9FAY6
      Conserved Domains (3) summary
      cd18419
      Location:6 → 143
      BTB_POZ_KCND3; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium voltage-gated channel subfamily D member 3 (KCND3)
      pfam00520
      Location:186 → 412
      Ion_trans; Ion transport protein
      pfam11879
      Location:442 → 544
      DUF3399; Domain of unknown function (DUF3399)
    Nucleotide Protein
    Heading Accession and Version

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