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    PTPRO protein tyrosine phosphatase receptor type O [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700811, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PTPROprovided by VGNC
    Official Full Name
    protein tyrosine phosphatase receptor type Oprovided by VGNC
    Primary source
    VGNC:VGNC:100096
    See related
    Ensembl:ENSMMUG00000032109
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PTPRO in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (16732542..17004141)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (16017713..16292211)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene RAS like estrogen regulated growth inhibitor Neighboring gene U6 spliceosomal RNA Neighboring gene 40S ribosomal protein S2 pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene EGFR pathway substrate 8, signaling adaptor Neighboring gene 28S ribosomal protein S7, mitochondrial pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Wnt-protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cadherin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in podocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of glomerular filtration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in GABA-ergic synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    receptor-type tyrosine-protein phosphatase O

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      16732542..17004141
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015151205.2 → XP_015006691.1  receptor-type tyrosine-protein phosphatase O isoform X2

      UniProtKB/TrEMBL
      F6TUI9, G7N6F5
      Related
      ENSMMUP00000026886.4, ENSMMUT00000028734.4
      Conserved Domains (3) summary
      cd00063
      Location:530 → 630
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14614
      Location:923 → 1167
      R-PTPc-O; catalytic domain of receptor-type tyrosine-protein phosphatase O
      pfam00041
      Location:435 → 521
      fn3; Fibronectin type III domain

    2. XM_015151204.2 → XP_015006690.1  receptor-type tyrosine-protein phosphatase O isoform X1

      UniProtKB/TrEMBL
      F6TUJ8, G7N6F5
      Related
      ENSMMUP00000026885.4, ENSMMUT00000028733.4
      Conserved Domains (3) summary
      cd00063
      Location:530 → 630
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14614
      Location:951 → 1195
      R-PTPc-O; catalytic domain of receptor-type tyrosine-protein phosphatase O
      pfam00041
      Location:435 → 521
      fn3; Fibronectin type III domain
    Nucleotide Protein
    Heading Accession and Version

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