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    SSH3 slingshot protein phosphatase 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712699, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SSH3provided by VGNC
    Official Full Name
    slingshot protein phosphatase 3provided by VGNC
    Primary source
    VGNC:VGNC:78019
    See related
    Ensembl:ENSMMUG00000015932
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SSH3 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (7213837..7222271, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (7077400..7086052, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene RAD9 checkpoint clamp component A Neighboring gene cardiotrophin like cytokine factor 1 Neighboring gene DNA polymerase delta 4, accessory subunit Neighboring gene ankyrin repeat domain 13D Neighboring gene G protein-coupled receptor kinase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine/serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase Slingshot homolog 3
    Names
    slingshot homolog 3
    NP_001253909.1
    XP_014969009.1
    XP_014969011.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266980.1 → NP_001253909.1  protein phosphatase Slingshot homolog 3

      See identical proteins and their annotated locations for NP_001253909.1

      Status: PROVISIONAL

      Source sequence(s)
      JU335170
      UniProtKB/TrEMBL
      F7AK49, G7NBY5
      Related
      ENSMMUP00000020963.1, ENSMMUT00000022404.3
      Conserved Domains (3) summary
      cd11652
      Location:3 → 259
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:329 → 464
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:272 → 320
      DEK_C; DEK C terminal domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      7213837..7222271 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015113525.2 → XP_014969011.1  protein phosphatase Slingshot homolog 3 isoform X2

      Conserved Domains (3) summary
      cd11652
      Location:3 → 259
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:329 → 464
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:272 → 320
      DEK_C; DEK C terminal domain

    2. XM_015113523.2 → XP_014969009.1  protein phosphatase Slingshot homolog 3 isoform X1

      UniProtKB/TrEMBL
      F7AK30, G7NBY5
      Related
      ENSMMUP00000020965.4, ENSMMUT00000022406.4
      Conserved Domains (3) summary
      cd11652
      Location:3 → 259
      SSH-N; N-terminal domain conserved in slingshot (SSH) phosphatases
      cd00127
      Location:329 → 464
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
      pfam08766
      Location:272 → 320
      DEK_C; DEK C terminal domain
    Nucleotide Protein
    Heading Accession and Version

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