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    LCP1 lymphocyte cytosolic protein 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 703429, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LCP1provided by VGNC
    Official Full Name
    lymphocyte cytosolic protein 1provided by VGNC
    Primary source
    VGNC:VGNC:74242
    Locus tag
    EGK_09301
    See related
    Ensembl:ENSMMUG00000017033
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    plastin-2
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See LCP1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 17 NC_041770.1 (24631509..24665423, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 17 NC_027909.1 (25352281..25386227, complement)

    Chromosome 17 - NC_041770.1Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH-type containing 13 Neighboring gene uncharacterized LOC114673524 Neighboring gene carboxypeptidase B2 Neighboring gene uncharacterized LOC106994255 Neighboring gene uncharacterized LOC114673577 Neighboring gene small nucleolar RNA U13 Neighboring gene leucine rich repeat containing 63

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament network formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in actin filament bundle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plastin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266307.1 → NP_001253236.1  plastin-2

      See identical proteins and their annotated locations for NP_001253236.1

      Status: PROVISIONAL

      Source sequence(s)
      JU334467
      UniProtKB/TrEMBL
      A0A8J8XV10, F7A8Z5, F7HQU5, G7NK35
      Related
      ENSMMUP00000036329.1, ENSMMUT00000043332.3
      Conserved Domains (5) summary
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd21292
      Location:98 → 242
      CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
      cd21327
      Location:251 → 375
      CH_PLS2_rpt2; second calponin homology (CH) domain found in plastin-2
      cd21333
      Location:511 → 625
      CH_PLS2_rpt4; fourth calponin homology (CH) domain found in plastin-2
      cl00030
      Location:374 → 507
      CH_SF; calponin homology (CH) domain superfamily

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041770.1 Reference Mmul_10 Primary Assembly

      Range
      24631509..24665423 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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