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    ERBIN erbb2 interacting protein [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700429, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ERBINprovided by VGNC
    Official Full Name
    erbb2 interacting proteinprovided by VGNC
    Primary source
    VGNC:VGNC:81395
    See related
    Ensembl:ENSMMUG00000007683
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ERBIN in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (64508254..64658829)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (64110940..64262115)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 13 Neighboring gene small glutamine rich tetratricopeptide repeat co-chaperone beta Neighboring gene neurolysin Neighboring gene T-cell leukemia/lymphoma protein 1B pseudogene Neighboring gene U6 snRNA-associated Sm-like protein LSm8 Neighboring gene splicing regulatory glutamic acid and lysine rich protein 1 Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neurotransmitter receptor transport postsynaptic membrane to endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein LAP2; erbin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      64508254..64658829
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028849477.1 → XP_028705310.1  erbin isoform X7

      UniProtKB/TrEMBL
      F7CEY3
      Conserved Domains (3) summary
      COG4886
      Location:70 → 402
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00992
      Location:1367 → 1453
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]

    2. XM_015140143.2 → XP_014995629.1  erbin isoform X2

      UniProtKB/TrEMBL
      F7CEY3
      Conserved Domains (5) summary
      cd00116
      Location:48 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd00992
      Location:1323 → 1409
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:368 → 411
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:345 → 402
      LRR_8; Leucine rich repeat

    3. XM_015140142.2 → XP_014995628.1  erbin isoform X1

      UniProtKB/TrEMBL
      F7CEY3, F7GX57
      Conserved Domains (5) summary
      cd00116
      Location:48 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd00992
      Location:1327 → 1413
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:368 → 411
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:345 → 402
      LRR_8; Leucine rich repeat

    4. XM_015140149.2 → XP_014995635.1  erbin isoform X6

      UniProtKB/TrEMBL
      A0A5F7ZYL0, A0A5F8ANR1
      Related
      ENSMMUP00000078713.1, ENSMMUT00000095966.1
      Conserved Domains (3) summary
      cd00116
      Location:48 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:345 → 402
      LRR_8; Leucine rich repeat

    5. XM_015140140.2 → XP_014995626.1  erbin isoform X1

      UniProtKB/TrEMBL
      F7CEY3, F7GX57
      Conserved Domains (5) summary
      cd00116
      Location:48 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd00992
      Location:1327 → 1413
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:368 → 411
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:345 → 402
      LRR_8; Leucine rich repeat

    6. XM_015140144.2 → XP_014995630.1  erbin isoform X3

      UniProtKB/TrEMBL
      F7CEY3, F7GX50
      Related
      ENSMMUP00000034596.1, ENSMMUT00000041569.3
      Conserved Domains (5) summary
      cd00116
      Location:48 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd00992
      Location:1279 → 1365
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:368 → 411
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:345 → 402
      LRR_8; Leucine rich repeat

    7. XM_015140146.2 → XP_014995632.1  erbin isoform X5

      UniProtKB/TrEMBL
      A0A1D5QYP9, F7GX54
      Related
      ENSMMUP00000034594.3, ENSMMUT00000041567.3
      Conserved Domains (4) summary
      cd00116
      Location:48 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd00992
      Location:1211 → 1296
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:345 → 402
      LRR_8; Leucine rich repeat

    8. XM_015140145.2 → XP_014995631.1  erbin isoform X4

      UniProtKB/TrEMBL
      F7CEY3
      Conserved Domains (5) summary
      cd00116
      Location:48 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd00992
      Location:1275 → 1361
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:368 → 411
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:345 → 402
      LRR_8; Leucine rich repeat

    9. XM_015140141.2 → XP_014995627.1  erbin isoform X1

      UniProtKB/TrEMBL
      F7CEY3, F7GX57
      Related
      ENSMMUP00000034592.3, ENSMMUT00000041565.3
      Conserved Domains (5) summary
      cd00116
      Location:48 → 209
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd00992
      Location:1327 → 1413
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00033
      Location:24 → 47
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:368 → 411
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:345 → 402
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version

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