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    ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif 20 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699935, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAMTS20provided by VGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 20provided by VGNC
    Primary source
    VGNC:VGNC:69444
    See related
    Ensembl:ENSMMUG00000013942
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADAMTS20 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (42782776..42999189, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (41317487..41575590, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107000837 Neighboring gene uncharacterized LOC114671054 Neighboring gene 52 kDa repressor of the inhibitor of the protein kinase pseudogene Neighboring gene elongation factor 1-alpha pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 20

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110539.3 → NP_001104009.3  A disintegrin and metalloproteinase with thrombospondin motifs 20 precursor

      Status: PROVISIONAL

      Source sequence(s)
      QNVO02000060
      UniProtKB/TrEMBL
      F6SF07, G7N6R0
      Related
      ENSMMUP00000018329.4, ENSMMUT00000019572.4
      Conserved Domains (7) summary
      smart00209
      Location:560 → 612
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:260 → 465
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      PTZ00441
      Location:1125 → 1211
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      pfam01562
      Location:40 → 185
      Pep_M12B_propep; Reprolysin family propeptide
      pfam05986
      Location:722 → 841
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08685
      Location:1715 → 1910
      GON; GON domain
      pfam17771
      Location:480 → 547
      ADAM_CR_2; ADAM cysteine-rich domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      42782776..42999189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028828834.1 → XP_028684667.1  A disintegrin and metalloproteinase with thrombospondin motifs 20 isoform X1

      UniProtKB/TrEMBL
      G7N6R0
      Conserved Domains (6) summary
      smart00209
      Location:488 → 540
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:188 → 393
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      PTZ00441
      Location:1053 → 1139
      PTZ00441; sporozoite surface protein 2 (SSP2); Provisional
      pfam05986
      Location:650 → 769
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam01562
      Location:2 → 113
      Pep_M12B_propep; Reprolysin family propeptide
      pfam08685
      Location:1643 → 1838
      GON; GON domain
    Nucleotide Protein
    Heading Accession and Version

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