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    CYBB cytochrome b-245 beta chain [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696542, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CYBBprovided by VGNC
    Official Full Name
    cytochrome b-245 beta chainprovided by VGNC
    Primary source
    VGNC:VGNC:71576
    Locus tag
    EGK_20383
    See related
    Ensembl:ENSMMUG00000013220
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CYBB in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (37571601..37605643)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (37525871..37559915)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene LanC like family member 3 Neighboring gene X-linked Kx blood group antigen, Kell and VPS13A binding protein Neighboring gene peptidyl-prolyl cis-trans isomerase D pseudogene Neighboring gene dynein light chain Tctex-type 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables superoxide-generating NAD(P)H oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in superoxide anion generation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of NADPH oxidase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome b-245 heavy chain
    Names
    cytochrome b-245, beta polypeptide (chronic granulomatous disease)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      37571601..37605643
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001083654.4 → XP_001083654.1  cytochrome b-245 heavy chain

      See identical proteins and their annotated locations for XP_001083654.1

      UniProtKB/TrEMBL
      A0A5F8AA85, A0A8J8YNE8, F6X7S5, G7NSZ5
      Related
      ENSMMUP00000017369.2, ENSMMUT00000018545.4
      Conserved Domains (3) summary
      cd06186
      Location:297 → 570
      NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
      pfam01794
      Location:66 → 219
      Ferric_reduct; Ferric reductase like transmembrane component
      cl26813
      Location:165 → 423
      PLN02844; oxidoreductase/ferric-chelate reductase
    Nucleotide Protein
    Heading Accession and Version

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