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    RASA4B RAS p21 protein activator 4B [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719871, updated on 5-Mar-2024

    Summary

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    Gene symbol
    RASA4B
    Gene description
    RAS p21 protein activator 4B
    See related
    Ensembl:ENSMMUG00000030384
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    RASA4
    Orthologs
    human all
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    Genomic context

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    See RASA4B in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (44603091..44638694, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (127883986..127917918, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeats and WD repeat domain containing 1 Neighboring gene RNA polymerase II subunit J Neighboring gene uroplakin 3B like 2 Neighboring gene uroplakin 3B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to calcium ion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ras GTPase-activating protein 4B
    Names
    RAS p21 protein activator 4
    ras GTPase-activating protein 4 pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      44603091..44638694 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028845630.1 → XP_028701463.1  ras GTPase-activating protein 4B isoform X2

      UniProtKB/TrEMBL
      F7DVY6, H9Z430
      Related
      ENSMMUP00000035403.2, ENSMMUT00000042401.3
      Conserved Domains (5) summary
      cd04025
      Location:62 → 185
      C2B_RasA1_RasA4; C2 domain second repeat present in RasA1 and RasA4
      cd05395
      Location:193 → 478
      RasGAP_RASA4; Ras-GTPase Activating Domain of RASA4
      cd13372
      Location:470 → 609
      PH_CAPRI; Ca2+ promoted Ras inactivator pleckstrin homology (PH) domain
      pfam00779
      Location:609 → 634
      BTK; BTK motif
      cl14603
      Location:1 → 54
      C2; C2 domain

    2. XM_028845631.1 → XP_028701464.1  ras GTPase-activating protein 4B isoform X3

      UniProtKB/TrEMBL
      H9Z430, I0FN97
      Conserved Domains (5) summary
      cd04025
      Location:134 → 257
      C2B_RasA1_RasA4; C2 domain second repeat present in RasA1 and RasA4
      cd04054
      Location:6 → 126
      C2A_Rasal1_RasA4; C2 domain first repeat present in RasA1 and RasA4
      cd05395
      Location:265 → 550
      RasGAP_RASA4; Ras-GTPase Activating Domain of RASA4
      cd13372
      Location:542 → 681
      PH_CAPRI; Ca2+ promoted Ras inactivator pleckstrin homology (PH) domain
      pfam00779
      Location:681 → 704
      BTK; BTK motif

    3. XM_028845629.1 → XP_028701462.1  ras GTPase-activating protein 4B isoform X1

      UniProtKB/TrEMBL
      A0A1D5QWN8, H9Z430
      Related
      ENSMMUP00000052468.2, ENSMMUT00000058025.2
      Conserved Domains (5) summary
      cd04025
      Location:134 → 257
      C2B_RasA1_RasA4; C2 domain second repeat present in RasA1 and RasA4
      cd04054
      Location:6 → 126
      C2A_Rasal1_RasA4; C2 domain first repeat present in RasA1 and RasA4
      cd05395
      Location:265 → 550
      RasGAP_RASA4; Ras-GTPase Activating Domain of RASA4
      cd13372
      Location:542 → 681
      PH_CAPRI; Ca2+ promoted Ras inactivator pleckstrin homology (PH) domain
      pfam00779
      Location:681 → 706
      BTK; BTK motif
    Nucleotide Protein
    Heading Accession and Version

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