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    LEMD2 LEM domain nuclear envelope protein 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718463, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LEMD2provided by VGNC
    Official Full Name
    LEM domain nuclear envelope protein 2provided by VGNC
    Primary source
    VGNC:VGNC:74097
    See related
    Ensembl:ENSMMUG00000021734
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LEMD2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (135696606..135714736)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (34634173..34652889, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene glutamate metabotropic receptor 4 Neighboring gene uncharacterized LOC106997913 Neighboring gene motilin Neighboring gene inositol hexakisphosphate kinase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear envelope organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LEM domain-containing protein 2
    Names
    LEM domain containing 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      135696606..135714736
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001116367.4 → XP_001116367.1  LEM domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      F7E2J4
      Related
      ENSMMUP00000028624.4, ENSMMUT00000030584.4
      Conserved Domains (2) summary
      pfam09402
      Location:284 → 499
      MSC; Man1-Src1p-C-terminal domain
      cl02649
      Location:4 → 41
      LEM; LEM (Lap2/Emerin/Man1) domain found in emerin, lamina-associated polypeptide 2 (LAP2), inner nuclear membrane protein Man1 and similar proteins

    2. XM_028847665.1 → XP_028703498.1  LEM domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      F7E2J4
      Conserved Domains (4) summary
      PHA03307
      Location:55 → 191
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam05672
      Location:36 → 92
      MAP7; MAP7 (E-MAP-115) family
      pfam09402
      Location:284 → 454
      MSC; Man1-Src1p-C-terminal domain
      cl02649
      Location:4 → 41
      LEM; LEM (Lap2/Emerin/Man1) domain found in emerin, lamina-associated polypeptide 2 (LAP2), inner nuclear membrane protein Man1 and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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