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    DEFA6 defensin alpha 6 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717000, updated on 5-Mar-2024

    Summary

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    Gene symbol
    DEFA6
    Gene description
    defensin alpha 6
    Locus tag
    EGK_18657
    See related
    Ensembl:ENSMMUG00000052512
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DEFA6 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (7659800..7661034, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (7088325..7089688, complement)

    Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene XK related 5 Neighboring gene uncharacterized LOC114680167 Neighboring gene defensin beta 1 Neighboring gene neutrophil defensin 4-like Neighboring gene demidefensin 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular evolution of the primate α-/θ-defensin multigene family. Cheng DQ, et al. PLoS One, 2014. PMID 24819937, Free PMC Article
    2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in antibacterial humoral response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to lipopolysaccharide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to Gram-negative bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to Gram-positive bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in disruption of plasma membrane integrity in another organism IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response in mucosa IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    defensin-6
    Names
    defensin, alpha 6, Paneth cell-specific

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041761.1 Reference Mmul_10 Primary Assembly

      Range
      7659800..7661034 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001098733.4 → XP_001098733.1  defensin-6

      See identical proteins and their annotated locations for XP_001098733.1

      UniProtKB/TrEMBL
      A0A5F7ZD38, A0A8J8Y0I9, F7DMC6
      Related
      ENSMMUP00000063497.1, ENSMMUT00000097813.1
      Conserved Domains (2) summary
      pfam00323
      Location:72 → 99
      Defensin_1; Mammalian defensin
      pfam00879
      Location:1 → 56
      Defensin_propep; Defensin propeptide
    Nucleotide Protein
    Heading Accession and Version

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