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    ADAM22 ADAM metallopeptidase domain 22 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705350, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAM22provided by VGNC
    Official Full Name
    ADAM metallopeptidase domain 22provided by VGNC
    Primary source
    VGNC:VGNC:69483
    Locus tag
    EGK_13962
    See related
    Ensembl:ENSMMUG00000022695
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADAM22 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (117932166..118179095, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (105858629..106105230, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene STEAP4 metalloreductase Neighboring gene sorcin Neighboring gene DBF4 zinc finger Neighboring gene solute carrier family 25 member 40 Neighboring gene uncharacterized LOC114676993

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    disintegrin and metalloproteinase domain-containing protein 22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      117932166..118179095 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846109.1 → XP_028701942.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X13

      UniProtKB/TrEMBL
      H9F832
      Conserved Domains (4) summary
      smart00608
      Location:437 → 578
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:146 → 345
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam00200
      Location:360 → 433
      Disintegrin
      pfam01562
      Location:15 → 95
      Pep_M12B_propep; Reprolysin family propeptide

    2. XM_028846114.1 → XP_028701947.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X18

      UniProtKB/TrEMBL
      H9F833
      Conserved Domains (4) summary
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam00200
      Location:453 → 526
      Disintegrin
      pfam01562
      Location:74 → 188
      Pep_M12B_propep; Reprolysin family propeptide

    3. XM_028846110.1 → XP_028701943.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X14

      UniProtKB/TrEMBL
      H9F833
      Conserved Domains (4) summary
      smart00050
      Location:453 → 528
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:71 → 188
      Pep_M12B_propep; Reprolysin family propeptide

    4. XM_028846108.1 → XP_028701941.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X12

      UniProtKB/TrEMBL
      H9F833
      Conserved Domains (4) summary
      smart00050
      Location:453 → 528
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:71 → 188
      Pep_M12B_propep; Reprolysin family propeptide

    5. XM_028846106.1 → XP_028701939.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X10

      UniProtKB/TrEMBL
      H9F833
      Conserved Domains (4) summary
      smart00050
      Location:453 → 528
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:71 → 188
      Pep_M12B_propep; Reprolysin family propeptide

    6. XM_028846107.1 → XP_028701940.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X11

      UniProtKB/TrEMBL
      H9F832
      Conserved Domains (4) summary
      smart00050
      Location:453 → 528
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:71 → 188
      Pep_M12B_propep; Reprolysin family propeptide

    7. XM_028846104.1 → XP_028701937.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X8

      UniProtKB/TrEMBL
      F7GSN2, H9F832
      Related
      ENSMMUP00000029881.4, ENSMMUT00000031937.4
      Conserved Domains (4) summary
      smart00050
      Location:453 → 528
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:71 → 188
      Pep_M12B_propep; Reprolysin family propeptide

    8. XM_028846105.1 → XP_028701938.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X9

      UniProtKB/TrEMBL
      H9F832
      Conserved Domains (4) summary
      smart00050
      Location:453 → 528
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:71 → 188
      Pep_M12B_propep; Reprolysin family propeptide

    9. XM_028846101.1 → XP_028701934.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X5

      UniProtKB/TrEMBL
      H9F832
      Conserved Domains (4) summary
      smart00050
      Location:453 → 528
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:71 → 188
      Pep_M12B_propep; Reprolysin family propeptide

    10. XM_028846099.1 → XP_028701932.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X3

      UniProtKB/TrEMBL
      H9F832
      Conserved Domains (4) summary
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam00200
      Location:453 → 526
      Disintegrin
      pfam01562
      Location:74 → 188
      Pep_M12B_propep; Reprolysin family propeptide

    11. XM_028846100.1 → XP_028701933.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X4

      UniProtKB/TrEMBL
      H9F832
      Conserved Domains (4) summary
      smart00608
      Location:529 → 670
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:238 → 437
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam00200
      Location:452 → 525
      Disintegrin
      pfam01562
      Location:73 → 187
      Pep_M12B_propep; Reprolysin family propeptide

    12. XM_028846102.1 → XP_028701935.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X6

      UniProtKB/TrEMBL
      H9F832
      Conserved Domains (4) summary
      smart00050
      Location:452 → 527
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:529 → 670
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:238 → 437
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:70 → 187
      Pep_M12B_propep; Reprolysin family propeptide

    13. XM_028846111.1 → XP_028701944.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X15

      UniProtKB/TrEMBL
      H9F833
      Conserved Domains (4) summary
      smart00608
      Location:529 → 670
      ACR; ADAM Cysteine-Rich Domain
      pfam00200
      Location:452 → 525
      Disintegrin
      pfam01421
      Location:238 → 437
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:70 → 187
      Pep_M12B_propep; Reprolysin family propeptide

    14. XM_028846098.1 → XP_028701931.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X2

      UniProtKB/TrEMBL
      G7MLY3
      Related
      ENSMMUP00000056081.2, ENSMMUT00000061650.2
      Conserved Domains (4) summary
      smart00050
      Location:505 → 580
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:582 → 723
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:291 → 490
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:123 → 240
      Pep_M12B_propep; Reprolysin family propeptide

    15. XM_028846097.1 → XP_028701930.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X1

      UniProtKB/TrEMBL
      G7MLY3
      Conserved Domains (4) summary
      smart00050
      Location:505 → 580
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:582 → 723
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:291 → 490
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:123 → 240
      Pep_M12B_propep; Reprolysin family propeptide

    16. XM_028846103.1 → XP_028701936.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X7

      UniProtKB/TrEMBL
      A0A5F8AHV2, G7MLY3
      Related
      ENSMMUP00000076542.1, ENSMMUT00000095638.1
      Conserved Domains (4) summary
      smart00050
      Location:505 → 580
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:582 → 723
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:291 → 490
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:123 → 240
      Pep_M12B_propep; Reprolysin family propeptide

    17. XM_028846113.1 → XP_028701946.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X17

      UniProtKB/TrEMBL
      H9F833
      Related
      ENSMMUP00000078920.1, ENSMMUT00000090989.1
      Conserved Domains (4) summary
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam00200
      Location:453 → 526
      Disintegrin
      pfam01562
      Location:74 → 188
      Pep_M12B_propep; Reprolysin family propeptide

    18. XM_028846112.1 → XP_028701945.1  disintegrin and metalloproteinase domain-containing protein 22 isoform X16

      UniProtKB/TrEMBL
      H9F832
      Related
      ENSMMUP00000029882.4, ENSMMUT00000031938.4
      Conserved Domains (4) summary
      smart00608
      Location:530 → 671
      ACR; ADAM Cysteine-Rich Domain
      pfam01421
      Location:239 → 438
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam00200
      Location:453 → 526
      Disintegrin
      pfam01562
      Location:74 → 188
      Pep_M12B_propep; Reprolysin family propeptide
    Nucleotide Protein
    Heading Accession and Version

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