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    MARK3 microtubule affinity regulating kinase 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695234, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MARK3provided by VGNC
    Official Full Name
    microtubule affinity regulating kinase 3provided by VGNC
    Primary source
    VGNC:VGNC:74659
    See related
    Ensembl:ENSMMUG00000003641
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MARK3 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (165692817..165811372)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (165741524..165860788)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene 40S ribosomal protein SA pseudogene Neighboring gene creatine kinase B Neighboring gene tRNA methyltransferase 61A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    MAP/microtubule affinity-regulating kinase 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      165692817..165811372
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015144547.2 → XP_015000033.1  MAP/microtubule affinity-regulating kinase 3 isoform X7

      UniProtKB/TrEMBL
      F6Q5N1, H9FUH1
      Related
      ENSMMUP00000004858.4, ENSMMUT00000005157.4
      Conserved Domains (3) summary
      cd12196
      Location:645 → 742
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    2. XM_015144550.2 → XP_015000036.1  MAP/microtubule affinity-regulating kinase 3 isoform X10

      UniProtKB/TrEMBL
      A0A1D5R0F8, F6Q5N1, H9FUG8
      Related
      ENSMMUP00000053791.2, ENSMMUT00000071848.2
      Conserved Domains (3) summary
      cd12196
      Location:630 → 727
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    3. XM_015144551.2 → XP_015000037.1  MAP/microtubule affinity-regulating kinase 3 isoform X11

      UniProtKB/TrEMBL
      F6Q5N1, H9YXQ1
      Conserved Domains (3) summary
      cd12196
      Location:614 → 711
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    4. XM_015144546.2 → XP_015000032.1  MAP/microtubule affinity-regulating kinase 3 isoform X6

      UniProtKB/TrEMBL
      F6Q5N1, H9FUH0
      Related
      ENSMMUP00000050840.2, ENSMMUT00000066956.2
      Conserved Domains (3) summary
      cd12196
      Location:654 → 751
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    5. XM_015144541.2 → XP_015000027.1  MAP/microtubule affinity-regulating kinase 3 isoform X1

      UniProtKB/TrEMBL
      G7MWG9
      Conserved Domains (4) summary
      cd12196
      Location:706 → 803
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:56 → 307
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    6. XM_015144543.2 → XP_015000029.1  MAP/microtubule affinity-regulating kinase 3 isoform X3

      UniProtKB/TrEMBL
      F6Q5N1
      Conserved Domains (4) summary
      cd12196
      Location:691 → 788
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:56 → 307
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    7. XM_015144542.2 → XP_015000028.1  MAP/microtubule affinity-regulating kinase 3 isoform X2

      UniProtKB/TrEMBL
      F6Q5N1, F6Q5Q2
      Related
      ENSMMUP00000004857.4, ENSMMUT00000005156.4
      Conserved Domains (4) summary
      cd12196
      Location:697 → 794
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:56 → 307
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    8. XM_015144545.2 → XP_015000031.1  MAP/microtubule affinity-regulating kinase 3 isoform X5

      UniProtKB/TrEMBL
      F6Q5N1
      Conserved Domains (4) summary
      cd12196
      Location:682 → 779
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:56 → 307
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    9. XM_015144548.2 → XP_015000034.1  MAP/microtubule affinity-regulating kinase 3 isoform X8

      UniProtKB/TrEMBL
      A0A1D5QHC2, F6Q5N1
      Related
      ENSMMUP00000047443.2, ENSMMUT00000062925.2
      Conserved Domains (3) summary
      cd12196
      Location:639 → 736
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    10. XM_015144544.2 → XP_015000030.1  MAP/microtubule affinity-regulating kinase 3 isoform X4

      UniProtKB/TrEMBL
      G7MWG9
      Conserved Domains (4) summary
      cd12196
      Location:690 → 787
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:56 → 307
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    11. XM_015144549.2 → XP_015000035.1  MAP/microtubule affinity-regulating kinase 3 isoform X9

      UniProtKB/TrEMBL
      F6Q5N1, H9FUG9
      Conserved Domains (3) summary
      cd12196
      Location:638 → 735
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      cd14407
      Location:325 → 367
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cd14072
      Location:55 → 307
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    12. XM_015144552.2 → XP_015000038.1  MAP/microtubule affinity-regulating kinase 3 isoform X12

      UniProtKB/TrEMBL
      F6Q5N1
      Conserved Domains (3) summary
      cd12196
      Location:575 → 672
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      cd14407
      Location:194 → 236
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cl21453
      Location:1 → 176
      PKc_like; Protein Kinases, catalytic domain

    13. XM_028851913.1 → XP_028707746.1  MAP/microtubule affinity-regulating kinase 3 isoform X12

      UniProtKB/TrEMBL
      F6Q5N1
      Conserved Domains (3) summary
      cd12196
      Location:575 → 672
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      cd14407
      Location:194 → 236
      UBA_MARK3_4; UBA domain found in MAP/microtubule affinity-regulating kinase MARK3, MARK4, and similar proteins
      cl21453
      Location:1 → 176
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
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