PREB prolactin regulatory element binding [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: PREBprovided by VGNC
Official Full Name: prolactin regulatory element bindingprovided by VGNC
Primary source: VGNC:VGNC:103847
See related: Ensembl:ENSMMUG00000002390
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	13	NC_041766.1 (81834047..81837922)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	13	NC_027905.1 (27409177..27413033, complement)

Chromosome 13 - NC_041766.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH35839 (e-PCR)
- UniSTS:87052

MARC_16971-16972:1020796411:1 (e-PCR)
- UniSTS:268167

STS-N81134 (e-PCR)
- UniSTS:54481

RH92602 (e-PCR)
- UniSTS:85218

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info	PubMed
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of COPII vesicle coating	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: guanine nucleotide-exchange factor SEC12; prolactin regulatory element-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001266941.1 → NP_001253870.1 guanine nucleotide-exchange factor SEC12

See identical proteins and their annotated locations for NP_001253870.1

Status: PROVISIONAL

Source sequence(s)

JV045839

UniProtKB/TrEMBL

F6PQ58, G7N9M7

Related

ENSMMUP00000003209.2, ENSMMUT00000003397.4

Conserved Domains (3) summary

COG2319
Location:143 → 336

WD40; WD40 repeat [General function prediction only]

sd00039
Location:164 → 196

7WD40; WD40 repeat [structural motif]

cl02567
Location:161 → 377

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041766.1 Reference Mmul_10 Primary Assembly

Range

81834047..81837922

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028831459.1 → XP_028687292.1 prolactin regulatory element-binding protein isoform X1

UniProtKB/TrEMBL

G7N9M7

Conserved Domains (2) summary

sd00039
Location:159 → 196

7WD40; WD40 repeat [structural motif]

cl29593
Location:160 → 224

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...