PRDX3 peroxiredoxin 3 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: PRDX3provided by VGNC
Official Full Name: peroxiredoxin 3provided by VGNC
Primary source: VGNC:VGNC:76394
See related: Ensembl:ENSMMUG00000008294
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	9	NC_041762.1 (119650023..119661022, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	9	NC_027901.1 (115129775..115140598, complement)

Chromosome 9 - NC_041762.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

RH11191 (e-PCR)
- UniSTS:22089

PRDX3_3538 (e-PCR)
- UniSTS:462459

PRDX3-1 (e-PCR)
- UniSTS:512648

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables thioredoxin peroxidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell redox homeostasis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to stress	IEA Inferred from Electronic Annotation more info	PubMed
involved_in hydrogen peroxide catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to oxidative stress	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: thioredoxin-dependent peroxide reductase, mitochondrial

NP_001252755.1

EC 1.11.1.15

EC 1.11.1.24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001265826.2 → NP_001252755.1 thioredoxin-dependent peroxide reductase, mitochondrial

See identical proteins and their annotated locations for NP_001252755.1

Status: PROVISIONAL

Source sequence(s)

JV600249

UniProtKB/TrEMBL

A0A1D5Q4H6, G7N189

Related

ENSMMUP00000042940.1, ENSMMUT00000056663.2

Conserved Domains (2) summary

PTZ00253
Location:69 → 255

PTZ00253; tryparedoxin peroxidase; Provisional

cd03015
Location:65 → 236

PRX_Typ2cys; Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. ...