MYL12A myosin, light chain 12A, regulatory, non-sarcomeric [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: MYL12A
Gene description: myosin, light chain 12A, regulatory, non-sarcomeric
See related: Ensembl:ENSMMUG00000019893
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: MYL12B
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Genomic context

Location:: chromosome: 18

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	18	NC_041771.1 (64476464..64484961)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	18	NC_027910.1 (6237629..6246163, complement)

Chromosome 18 - NC_041771.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH48209 (e-PCR)
- UniSTS:67166

GDB:451607 (e-PCR)
- UniSTS:157325

RH69715 (e-PCR)
- UniSTS:11734

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in platelet aggregation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: myosin, light chain 12A, regulatory, non-sarcomeric

Names: myosin regulatory light chain 12A; myosin regulatory light chain 12B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001257736.1 → NP_001244665.1 myosin, light chain 12A, regulatory, non-sarcomeric

See identical proteins and their annotated locations for NP_001244665.1

Status: PROVISIONAL

Source sequence(s)

JU332489

UniProtKB/TrEMBL

F7AEV1, F7GQJ2, H9FNV5

Conserved Domains (1) summary

COG5126
Location:18 → 168

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041771.1 Reference Mmul_10 Primary Assembly

Range

64476464..64484961

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028837854.1 → XP_028693687.1 myosin, light chain 12A, regulatory, non-sarcomeric isoform X2

UniProtKB/TrEMBL

F7AEV1, F7GQJ2, H9FNV5

Conserved Domains (1) summary

COG5126
Location:18 → 168

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
XM_015121628.2 → XP_014977114.1 myosin, light chain 12A, regulatory, non-sarcomeric isoform X2

UniProtKB/TrEMBL

F7AEV1, F7GQJ2, H9FNV5

Related

ENSMMUP00000041314.2, ENSMMUT00000048279.3

Conserved Domains (1) summary

COG5126
Location:18 → 168

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
XM_028837853.1 → XP_028693686.1 myosin, light chain 12A, regulatory, non-sarcomeric isoform X2

UniProtKB/TrEMBL

F7AEV1, F7GQJ2, H9FNV5

Related

ENSMMUP00000067737.1, ENSMMUT00000091244.1

Conserved Domains (1) summary

COG5126
Location:18 → 168

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
XM_015121627.2 → XP_014977113.1 myosin, light chain 12A, regulatory, non-sarcomeric isoform X1

UniProtKB/TrEMBL

F6T8J2, H9FNV5

Related

ENSMMUP00000071474.1, ENSMMUT00000103096.1

Conserved Domains (3) summary

COG5126
Location:24 → 174

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

cd00051
Location:38 → 82

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

cl08302
Location:108 → 169

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...